Protein Alignment alpha-Est4 and ces2b

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_021326380.1
• Gene: ces2b / 561967
• ZFINID: ZDB-GENE-041014-96
• Length: 1611
• Species: Danio rerio
• Alignment Length: 523
• Identity: 154/523 - (29%)
• Similarity: 241/523 - (46%)
• Gaps: 70/523 - (13%)

  Fly     7 EDAPVVQTTHGKVRGILLKSL-YDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLS 70
            ||.|::||..|.::|:.:|:. .|...:::.|||:|.||:|.||...|...:.|.|:||.:|...
Zfish    26 EDGPILQTNSGALKGLQMKARGKDTVIHSYLGIPFAKPPVGPLRLAPPQPAEKWEGVRDATKQPL 90

  Fly    71 KCLQVSTLTKE-----------VEGSEDCLYLNISVKTLNG--DPMPVMVYIHGGAFKGGDSSRR 122
            .|||...|.::           |:.||||||||:...:..|  |.:||||:||||.|....:|..
Zfish    91 MCLQDRQLVEDLVANLSAKVDMVDSSEDCLYLNVYTPSKPGRNDKLPVMVWIHGGGFTTCSASLF 155

  Fly   123 AWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPER 187
            . |......::||.:.|.:|||.|||.|..|.:  .|||.||.|.:.||:|::.|..:|.|||..
Zfish   156 D-GHVLAAYQDVVVVVIQYRLGLLGFFSTGDEN--APGNYGLLDQVAALQWVQENIHSFGGDPGS 217

  Fly   188 ITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFS-----MELNRLPQMEYRLAKHLG-YEGDN 246
            :||||.|:|.::|.|.:.||.|..||||||..:|.:     |.:|.||     :|:.:| ..|.:
Zfish   218 VTIFGESAGGISVSLHVLSPLSANLFHRAIAESGTAAMEAIMNVNPLP-----IAQAIGNASGCD 277

  Fly   247 VDS--QVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWS 309
            :.|  ::::.|::.....|:......||.:       |..:|:....|...     .:|.::...
Zfish   278 ISSTKKIVDCLMQKSEVEILKITMENPLFR-------FGVTIDGQFLPRPA-----AELFQSQQF 330

  Fly   310 NRIPIILGANSGEGMSIFSFVKMN----PSWLKEFQCNPERVLPWTLRNRCDPG-QRRQLGQALI 369
            |::|::.|....|    ..||..|    |.|:.....  |.:||  |....:|. |.:.:.:.|:
Zfish   331 NKVPLMTGVTDDE----IGFVLPNYLLPPDWINGLDL--ESILP--LLTVFNPALQDQSVLELLL 387

  Fly   370 HHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRF 434
            :.:.......:.:  .:|..|:......:...|...|......||.|:|.|..........|..|
Zfish   388 NEYLGTSPDRIRI--RDGFREMLGDFMFNIPARQTASYHRDAGAPVYVYEFRHPPSVLQRKRPSF 450

  Fly   435 MGKEQRGVGHVDELGYIF-----KLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSL 494
            .|.:     |.||:.::|     :.|.....:.|..|....|..:|.:..||.|.:||.|   .|
Zfish   451 SGSD-----HGDEIVFVFGYCFSEGPIGMAENLSDEEDELCRTTMAYWGNFAHTGNPNGP---GL 507

  Fly   495 VDW 497
            ..|
Zfish   508 TSW 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	153/522 (29%)
ces2b	XP_021326380.1	COesterase	27..539	CDD:395084	153/522 (29%)
		COesterase	553..1065	CDD:395084
		COesterase	1079..1592	CDD:395084