Protein Alignment alpha-Est4 and nlgn4xa

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_021330915.1
• Gene: nlgn4xa / 561122
• ZFINID: ZDB-GENE-100309-2
• Length: 844
• Species: Danio rerio
• Alignment Length: 617
• Identity: 174/617 - (28%)
• Similarity: 249/617 - (40%)
• Gaps: 158/617 - (25%)

  Fly    10 PVVQTTHGKVRGI-------LLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSK 67
            |:|.|.:||:||:       :|..:  ||:.   |||||:||.|..||:.|.....|.|||:.::
Zfish    43 PIVTTNYGKLRGLKTPLPNEILGPV--EQYL---GIPYALPPTGERRFQPPEPPMSWPGIRNATQ 102

  Fly    68 PLSKCLQV--------------------STLTKEVEGSEDCLYLNISVKTLN-----GDPM---- 103
            ....|.|.                    :.:|...:.|||||||||.|.|.:     ||..
Zfish   103 FAPVCPQFLEDRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDVGANKGDDFTNNE 167

  Fly   104 --------------PVMVYIHGGAFKGG-----DSSRRA-WGPDYFMKENVVYISIGHRLGPLGF 148
                          |||||||||::..|     |.|..| :|       ||:.:::.:|||.|||
Zfish   168 GGENKDIHDENGLRPVMVYIHGGSYMEGTGNMIDGSILASYG-------NVIVVTLNYRLGVLGF 225

  Fly   149 LSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLF 213
            ||..|.  ...||.||.|.|.|||||:.|...|.|||:|:||||..:|:..|.||..|..||.||
Zfish   226 LSTGDQ--AAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLF 288

  Fly   214 HRAILLAGFSME---LNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKR 275
            .:||:.:|.::.   :|      |:.||:.....:.|...:|:           |.|....|:
Zfish   289 QKAIIQSGTALSSWAVN------YQPAKYTRILAEKVGCNMLD-----------SIDLVECLQ-- 334

  Fly   276 QGHNMPFKPSIESYST------------PNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFS 328
               |..:|..||.|.|            ...|:..:|..|..........|:||.|.|||   |.
Zfish   335 ---NKNYKELIEQYITQAKYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---FK 393

  Fly   329 FVKMNPSWLKEFQCNPERVLPWTLRNRCD-----PGQRRQLGQALIHHFCEAHGHELTVDHTNGL 388
            ||............|.   ..:.:.:..|     |..:..|.:.:...:.:....|........|
Zfish   394 FVDGIVDSEDGVSAND---FDFAVSDFVDHLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTL 455

  Fly   389 VELFT-HGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRF-MGKEQRGVGHVDELGYI 451
            |.||| |.:|............|| :|||.|.|        ::..:. |........|.||:.|:
Zfish   456 VALFTDHQWVAPAVATADLHAQYG-SPTYFYAF--------YHHCQSEMKPSWSDSAHGDEVPYV 511

  Fly   452 FKLPA-----TFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTK--SLVDWKPVTRFGKRMVL 509
            |.:|.     .|..:.|:.:......::..:..||.|.|||.|:.:  ..:..|| .||
Zfish   512 FGIPMLGPTDLFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP-NRF------ 569

  Fly   510 NISEEL---KFIPQPEMPKLKFFDRLYEMAGV 538
               ||:   |:.|:         |:||...|:
Zfish   570 ---EEVAWSKYNPK---------DQLYLHIGL 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	170/606 (28%)
		Aes	<104..>219	CDD:223730	57/120 (48%)
nlgn4xa	XP_021330915.1	COesterase	43..605	CDD:306613	174/617 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740