Protein Alignment alpha-Est4 and ces3

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 584
• Identity: 153/584 - (26%)
• Similarity: 239/584 - (40%)
• Gaps: 131/584 - (22%)

  Fly     7 EDAPVVQTTHGKVRGILLKS----LYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSK 67
            :..|||...||.|||..:|:    ...||:.   |||:|.||:|..|...|..::.|.|||:.::
Zfish    24 DSGPVVVLKHGSVRGQYVKAKGSPAVVEQYL---GIPFAQPPVGPHRLAAPQPVQGWEGIRNATE 85

  Fly    68 PLSKCLQ--------VSTLTKEVEG---SEDCLYLNISV--KTLNGDPMPVMVYIHGGAFKGGDS 119
            ..|.|||        ..::|.|:..   ||||||||:..  :....|..||||:|||||...|.:
Zfish    86 YSSMCLQDPNIVPKYAKSMTLELPPTGVSEDCLYLNVYTPSQRSESDKFPVMVWIHGGALVIGGA 150

  Fly   120 SRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGD 184
            .... |......|.||.:.|.:|||.||:||..|...:  ||.|..|.|.||:|::.|...|.||
Zfish   151 CMYD-GTPLAAYEKVVVVVIQYRLGILGYLSTGDQHAQ--GNWGFLDQIAALQWVQQNIEAFGGD 212

  Fly   185 PERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDS 249
            |:.:||.|.|:|.::..||..||.::|||.|||..:|.:            ..|...::.....:
Zfish   213 PQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVA------------TVKGYSFKDPLTYA 265

  Fly   250 QVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAV-----LLAEPIDLQRTTWS 309
            :|:..:.:.|   ..|::......:........|.:.:.|..|.|.     :.|:|.::.::...
Zfish   266 KVIANITECD---FSSSEVLVKCIREMTEEQIIKAAQKKYRLPGATVDGEFIKAQPEEILKSKDF 327

  Fly   310 NRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDP-----GQRRQLGQALI 369
            .:|||::|..:.|                         ..|||.:...|     |...:..:..:
Zfish   328 PKIPILVGTTNHE-------------------------FGWTLSHAILPKDWAKGMDAKSAKQTL 367

  Fly   370 HHFCEAHGHELTVDHTNGLV--ELFTH---------GFVHAMDRLIQ-----SRLTYGQ---APT 415
            ..|..|...|     .||::  |.|.:         .|...:..:|.     ...:|.:   ||.
Zfish   368 DFFYNAGASE-----ANGIIADEYFKNAKTPEEIRDAFTELLGDIIMVIPSIKVASYHRDAGAPV 427

  Fly   416 YLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIF---------KLPATFKLDKSRPEFTAIR 471
            |:|.|.......|.:|..|:..:     |.||:|::|         |:..|.    :..|....|
Zfish   428 YMYEFQHGPSIANKFRPSFVKAD-----HGDEIGFMFGACFWDGQVKVTGTL----TEEENQLCR 483

  Fly   472 RLVAMFVQFAATSDPN-APLTKSLVDWKPVTRFGKRMVLNI---------SEELKFIPQPEMPK 525
            .::..:..|..|..|| ||     |.|....:..|.:.|.:         .::|.|..: |:||
Zfish   484 TVMKYWANFVRTGSPNPAP-----VPWPVYDQSNKYLNLGLQQTEGQGLKKDKLLFFTE-ELPK 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	153/584 (26%)
		Aes	<104..>219	CDD:223730	51/114 (45%)
ces3	NP_001038401.1	COesterase	24..535	CDD:278561	149/575 (26%)
		Aes	<122..>235	CDD:223730	44/115 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575344
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840