DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est4 and Aadacl4fm2

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:XP_578509.2 Gene:Aadacl4fm2 / 502999 RGDID:1563334 Length:411 Species:Rattus norvegicus


Alignment Length:253 Identity:55/253 - (21%)
Similarity:83/253 - (32%) Gaps:92/253 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 CSKPLSKC-LQVSTLTKEVEGSEDCLYLNISVKTLNGDPMPV---------------MVYIHGGA 113
            ||.|...| ||...::|...|        :.||.|:...:||               :::.|||.
  Rat    65 CSMPRFFCFLQDLLVSKNNFG--------VLVKNLHFGTIPVRLFQPKTTSSGPRRGIIFYHGGG 121

  Fly   114 --FKGGDSSRRAWGPDYFMKE-NVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIR 175
              |.|.|......  .|...| :.|.:|:|:|         ..||...|  ...:|.:.|.....
  Rat   122 CMFGGLDCYHNLC--SYLASETDSVLLSVGYR---------KLPDHHHP--IVYQDCLNATIHFL 173

  Fly   176 ANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHL 240
            .....:..|||::.|.|.|.|:                ..|.::|...::...||:..       
  Rat   174 KELKTYGIDPEQVVISGESIGA----------------GAAAIIAQALLDRKDLPKFR------- 215

  Fly   241 GYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLA 298
                    :|||     .:|.:             ||.|... ||.:.|  |||..|:
  Rat   216 --------AQVL-----INPVI-------------QGINFQL-PSYQQY--PNAPFLS 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 55/253 (22%)
Aadacl4fm2XP_578509.2 alpha/beta hydrolases 114..379 CDD:473884 42/196 (21%)

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