Protein Alignment alpha-Est4 and Cesl1

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_063134329.1
• Gene: Cesl1 / 501232
• RGDID: 1565666
• Length: 596
• Species: Rattus norvegicus
• Alignment Length: 605
• Identity: 167/605 - (27%)
• Similarity: 250/605 - (41%)
• Gaps: 155/605 - (25%)

  Fly    10 PVVQTTHGKVRGILLKSL--YDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRD-------C 65
            |||.|..|||.| ...||  ..:....|.|:|:|.||||:|||..|...:||..:::       |
  Rat    59 PVVDTMKGKVLG-KYASLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMC 122

  Fly    66 SKPLSKCLQVSTL---TKE---VEGSEDCLYLNISVKT--LNGDPMPVMVYIHGGAFKGGDSSRR 122
            |:..:|..:::.|   .||   ::.|||||||||....  .....|||||:||||....|.:|..
  Rat   123 SQDATKGQRMNDLLTNRKEKVHLQFSEDCLYLNIYTPADFTKDSRMPVMVWIHGGGLTQGGASTY 187

  Fly   123 AWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPER 187
            . |......||||.::|.:|||..||.|..|....  ||.|..|.:.||.|::.|.|||.|||..
  Rat   188 D-GQVLSAYENVVVVAIQYRLGIWGFFSTGDEHSR--GNWGHLDQVAALHWVQDNIANFGGDPGS 249

  Fly   188 ITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG-------FSMELNRLPQMEYRLAKHLGYE-- 243
            :||||.|:|..:|.:|:.||.|:.|:||||..:|       |:.::....:   ::|...|.:
  Rat   250 VTIFGESAGGFSVSVLVLSPLSKNLYHRAISESGVVLITELFTKDVRPAAK---QIADMAGCKTT 311

  Fly   244 ---------GDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESY---ST--PNA 294
                     ....:.::||.:.|.:...:.|.                :.:.|||   ||  .:.
  Rat   312 TSAIIVHCLRQKTEEELLEIMEKMNLIKLSSQ----------------RDTKESYHFLSTVIDDV 360

  Fly   295 VLLAEPIDLQRTTWSNRIPIILGANSGE-GM---SIFSFV--------KMNPSWLKEFQC---NP 344
            ||..:|.::......|.:|.|:|.|..| |.   ::..||        ||....|::|..   .|
  Rat   361 VLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMRFVPPDVKLDKKMAIMLLEKFASIYGIP 425

  Fly   345 ERVLPWTL----RNRCDPGQRRQ-----LGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAM 400
            |.::|..:    :...||.:.|.     :|.||   || .....::.||.:
  Rat   426 EDIIPVAIEKYRKGSDDPIKIRDGILAFIGDAL---FC-IPSVMVSRDHRD-------------- 472

  Fly   401 DRLIQSRLTYGQAPTYLYRF----DFDSPDFNFYRIRFMGKEQRGVG-HVDELGYIFKLPATFKL 460
                      ..||||:|.:    .|.||.          :.:..|| |.|::..:|..| ..:.
  Rat   473 ----------AGAPTYVYEYQYYPSFSSPQ----------RPKDVVGDHADDVYSVFGAP-ILRD 516

  Fly   461 DKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNI-----------SEE 514
            ..|..|....:.::..:..||...:||.   :.|..|....:  |...|.|           :||
  Rat   517 GASEEEIKLSKMVMKFWANFARNGNPNG---RGLPHWPQYDQ--KEEYLQIGATTQQSQGLKAEE 576

  Fly   515 LKF--------IPQPEMPKL 526
            :.|        .|||...:|
  Rat   577 VAFWTQLLAKRQPQPHHNEL 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	167/605 (28%)
Cesl1	XP_063134329.1	None