Protein Alignment alpha-Est4 and Ces2h

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001037723.1
• Gene: Ces2h / 498940
• RGDID: 1560889
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 161/530 - (30%)
• Similarity: 237/530 - (44%)
• Gaps: 93/530 - (17%)

  Fly    12 VQTTH-GKVRGIL--LKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCL 73
            ::||| |::.|.|  :|.| |...::|.|||:|.||:|.|||..|...:||.|:||.:...:.||
  Rat    32 IRTTHTGQILGSLIHMKGL-DVGVHSFLGIPFAKPPIGPLRFAPPEAPEPWSGVRDGTSHPAMCL 95

  Fly    74 Q-VSTLTKE-----------VEGSEDCLYLNISVKTLN----GDPMPVMVYIHGGAFKGG----- 117
            | ::.:..:           :..|||||||||  .|.|    |..:||||:|||||...|
  Rat    96 QDITAMNMQAFKLLKLTLPLIPMSEDCLYLNI--YTPNHAHEGSNLPVMVWIHGGALVIGMASLY 158

  Fly   118 DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFN 182
            |.|..|      ..||||.::|.:|||.|||.|..|.  ...||.|..|.:.||.|::.|.|:|.
  Rat   159 DGSMLA------AMENVVVVTIQYRLGVLGFFSTGDQ--HARGNWGYLDQVAALHWVQQNIAHFG 215

  Fly   183 GDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRL---PQMEYRLAKHL-GYE 243
            |:|:|:||||.|:|..:|...:.||.|.||||.||:.:|.::..:.:   ..:.||...:| |.|
  Rat   216 GNPDRVTIFGESAGGTSVSSHVVSPMSRGLFHGAIMESGVALMSSLISVSSDVVYRTVANLSGCE 280

  Fly   244 GDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTW 308
              .|||:.|...|:....           |:....|..|:  |.|.......|...|.:|..:..
  Rat   281 --QVDSKALVNCLRGKSE-----------EEIMSINKAFR--IISGIVDGIFLPRHPKELLASAD 330

  Fly   309 SNRIPIILGANSGE-GMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQ------RRQLGQ 366
            .:.||.|:|.|:.| |..|.|.:....|..|..:...:.:|...:.....|.:      ...:|.
  Rat   331 FHPIPSIIGVNNDEYGWIIPSSMTTTDSKKKMDRQMVQAILQKRVAQMMWPPEFSDLLLEEYMGD 395

  Fly   367 ALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYR 431
            :....|.:....|:..|            |...:..|..:......||.|.|.|. ..|.|
  Rat   396 SEDPQFLQVQFKEMMED------------FTFVIPALQVAHFQRSNAPVYFYEFQ-HRPSF---- 443

  Fly   432 IRFMGKEQRGV--GHVDELGYIFKLPATF----KLDKSRPEFTAIRRLVAMFVQFAATSDPNAPL 490
              |...:...|  .|.||:.:||:   :|    ::|.:..|....||::..:..||...:||
  Rat   444 --FKDSKPPHVKADHGDEILFIFR---SFWGGTQVDLTEEEELLSRRMMKYWANFARQGNPN--- 500

  Fly   491 TKSLVDWKPV 500
            ::.|..| ||
  Rat   501 SEGLPYW-PV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	161/530 (30%)
Ces2h	NP_001037723.1	COesterase	30..537	CDD:395084	161/530 (30%)