Protein Alignment alpha-Est4 and LOC4576531

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_315381.5
• Gene: LOC4576531 / 4576531
• VectorBaseID: AGAMI1_014228
• Length: 1170
• Species: Anopheles gambiae
• Alignment Length: 567
• Identity: 159/567 - (28%)
• Similarity: 255/567 - (44%)
• Gaps: 116/567 - (20%)

  Fly     7 EDAPVVQTTHGKV----RGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPH-DLKPWHGIRDCS 66
            |..|||.|.:|.:    ||         .:|||:|||||.||.|..||..|. :.:.|...|:.:
Mosquito    30 EQPPVVHTENGPIVGEKRG---------NYYAFEGIPYAKPPTGERRFAAPELNDERWSEPRNAT 85

  Fly    67 KPLSKCLQVS-TL--TKEVEGSEDCLYLNISVKTLNGDP----MPVMVYIHGGAFKGGDSSRRAW 124
            .....|||.| |:  ..::.|:|||||:||...:|:|..    :..:.|||||||..|...  .:
Mosquito    86 TIGPYCLQWSHTIPGKDKLFGAEDCLYMNIYTTSLDGGQRQTGLSTLFYIHGGAFMFGGGG--LF 148

  Fly   125 GPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERIT 189
            .|::.:::..:.::..:|||||||||..| |: ||||.||||.:.||:|:|.|..:|.|||||||
Mosquito   149 SPNHVLRKPKIMVTFNYRLGPLGFLSTED-DI-VPGNFGLKDQVAALQWVRKNIHHFGGDPERIT 211

  Fly   190 IFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHL----GYEGDNVDS- 249
            :.|.|:|..:|.|...||.|.|||...|..:|.::....:.:...|.||.:    |...|.:.|
Mosquito   212 LVGFSAGGASVHLHYLSPMSRGLFQNGIAHSGTALNPWVMAEDSARKAKQIARGVGCPEDRLSSS 276

  Fly   250 ---------QVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKP---SIESYSTPN--AVLLAEP 300
                     :..|.:::..|.|:   |:.        :| ||.|   .:|..|..|  ..|...|
Mosquito   277 QAMVECLRERTAEDIVRQVPFLL---DYL--------YN-PFSPLGVVVEKQSKVNRRPFLADHP 329

  Fly   301 IDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRC---DPGQRR 362
            ..|.|.....::|::|....|||:...:....|..:|.:.......:||..|..:.   |..:|.
Mosquito   330 AVLSRKGKLTKVPLVLSVTQGEGLYPGAEFVSNLDYLADIDARWHDLLPSILDYKSAVPDDKRRA 394

  Fly   363 QLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHA----MDRLIQSRLTYGQAPTYLYRFDF- 422
            :|..|:..|:. .:..:|::|:....|.:.::....|    ..:|:|..:     |.|.|.|::
Mosquito   395 ELSNAISEHYF-GNDRKLSIDNFRDFVSILSNRLFFAGVTKTAKLLQPHI-----PVYFYYFNYK 453

  Fly   423 ----------DSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMF 477
                      .:.|.|:           ||.|.:::  :...|.  ::..:.|......|:||.|
Mosquito   454 TVYGIGELMSGTEDVNY-----------GVAHGEDV--LLSFPT--RMRDNHPLTKGELRVVASF 503

  Fly   478 VQ----FAATSDPNAPLTKSLVDWKPVTRFGKRM--VLNISEELKFI 518
            |.    |:...:|               ::|..:  |.|||.:|:::
Mosquito   504 VDLYDTFSQGQEP---------------KYGNYLLPVQNISGQLRYM 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	158/566 (28%)
LOC4576531	XP_315381.5	None