Protein Alignment alpha-Est4 and LOC4576397

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_001237723.3
• Gene: LOC4576397 / 4576397
• VectorBaseID: AGAMI1_007721
• Length: 597
• Species: Anopheles gambiae
• Alignment Length: 585
• Identity: 176/585 - (30%)
• Similarity: 259/585 - (44%)
• Gaps: 122/585 - (20%)

  Fly     8 DAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPW-HGIRDCSKPLSK 71
            |||.|....|.:.|.|...:..|||.||.|||:|.||:|.|||.:|....|| ..:.:.|.....
Mosquito    53 DAPRVCIDDGCLVGTLRDGMGGEQFEAFLGIPFAQPPVGELRFADPLPNGPWFEQLYNASYERDM 117

  Fly    72 CLQVSTL--TKEVEGSEDCLYLNISVKTLNGD--PMPVMVYIHGGAFKGGDSSRRAWGPDYFM-K 131
            |||.:.|  ...|.|||||||||:.......|  .:||:||||||.|..|.:|....||:|.: .
Mosquito   118 CLQRNDLLPNPPVTGSEDCLYLNVYRPKECDDRTNLPVIVYIHGGGFFSGTASSLIVGPEYILDT 182

  Fly   132 ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSG 196
            :..:.:::.:|||.|||||..  |...|||.||||..|||||::.|...|.|:.:.|||.|.|:|
Mosquito   183 KRAILVTVQYRLGVLGFLSTG--DTAAPGNFGLKDQTLALRWVKRNIRRFGGNEQLITIVGQSAG 245

  Fly   197 SMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQME-YRLAKHLGYEGDNVDSQVLEFLLKADP 260
            :.:|.:.:.||.|.|||.|||:::|.|:....:|..: ..||:......|.:.:.      :...
Mosquito   246 AASVHMHMISPLSRGLFERAIMMSGNSLVPWNIPTKDPLALARSTAMVVDVMGAD------RLSG 304

  Fly   261 ALIVSADFFTPLEKRQG--HNMP---------FKPSIESYSTPNAVLLAEPIDLQRTTWSN---- 310
            ..:|:|....|.||..|  |.:.         |:|.:|...:||..|..||    :.:|.|
Mosquito   305 KQLVAALRDIPGEKLVGNVHKLKLWSVDPLTLFRPVVEPKDSPNPFLTEEP----KVSWRNGNYQ 365

  Fly   311 RIPIILGANSGEG----MSIF-----------SFVKMNPSWLKEFQCNPERVLPWTLRNRC---- 356
            ::|.:.|....||    :|||           :|..:.|..|::   .|.:.|...:|.||
Mosquito   366 QVPYLAGFVPNEGAIRALSIFKDATLFGELQRNFSTILPILLEQ---PPSKALTEKMRTRCLNDT 427

  Fly   357 -DPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTH-GFVHAMDRLIQSRLTYG---QAPTY 416
             |....||                   |:..|.|:|::. .|::.:...::..:|..   :||..
Mosquito   428 TDDEPVRQ-------------------DNLQGFVDLYSEAAFIYPVQLGVRQYITAADTDRAPAS 473

  Fly   417 LYRFDF-------------DSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATF-KLDKSRPEF 467
            :|:..:             |:.|:             ||.|.|:|.|:|:.||.| ......||.
Mosquito   474 VYKLSYKGRYSYSAIYAGGDTSDY-------------GVVHCDDLNYLFRQPAIFPDYPAGAPEL 525

  Fly   468 TAIRRLVAMFVQFA--ATSDPNAPLT---------KSL-VDWKPVTRFGKRM---VLNISEELKF 517
            ..:...|..|:.||  ..:.|.||:.         :|| .|.:...|.|..:   |||...|..|
Mosquito   526 KMVDTFVNFFIDFAINGRATPLAPVRECRNENQVYQSLDCDVQEFVRVGDDVQVKVLNARNEEMF 590

  Fly   518  517
            Mosquito   591  590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	176/585 (30%)
LOC4576397	XP_001237723.3	None