Protein Alignment alpha-Est4 and LOC4576396

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_315859.4
• Gene: LOC4576396 / 4576396
• VectorBaseID: AGAMI1_006793
• Length: 574
• Species: Anopheles gambiae
• Alignment Length: 587
• Identity: 182/587 - (31%)
• Similarity: 264/587 - (44%)
• Gaps: 93/587 - (15%)

  Fly     7 EDAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSK---- 67
            |:.|.|....|.:||..::||:.|::.||.|||:|.||:|.|||..|...:||...::...
Mosquito    19 ENVPRVCIQDGCMRGSWMRSLHGERYEAFIGIPFAKPPVGPLRFANPVPNEPWADRQELDASGRI 83

  Fly    68 PLSKCLQVSTLTKE--VEGSEDCLYLNI-------SVKTLNG-DPMPVMVYIHGGAFKGGDSSRR 122
            |.:.|||.:....|  |||.|||||||:       ...|.|| .|:..:||||||.|..|.:|..
Mosquito    84 PRAPCLQKNLFLPERGVEGKEDCLYLNVYRPFKVSKEGTENGTTPLATLVYIHGGGFLAGYNSPL 148

  Fly   123 AWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPER 187
            ..|.:..|...|:.::|.:|||..||||..|.  ...||.||||...||||:|.|...|.||||.
Mosquito   149 VAGAEKLMDNAVILVTIAYRLGAFGFLSTGDD--AASGNFGLKDQREALRWVRRNIEAFGGDPEL 211

  Fly   188 ITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLP-----QMEYRLAKHLGYEGDNV 247
            :|:.|||:|..:|.|.|....:||||.|||.|:|.::.....|     |:..:.|:.||.:....
Mosquito   212 VTVMGHSAGGASVHLQLMHLGNEGLFQRAISLSGNALTPWSAPRANPLQLAQQQARLLGIKKPQK 276

  Fly   248 DS--QVLEFLLKADPALIVSA-DFFTPLEKRQGHNMP---FKPSIESYSTPNAVLLAEPIDLQRT 306
            .|  :::|.|...|..|.||: ..||     .|...|   :.|.:|:.:.|:|.|...|    |.
Mosquito   277 MSSGELVEALRAIDADLFVSSYKGFT-----NGSRYPVIVYGPVVEAATVPDAFLTEPP----RE 332

  Fly   307 TWSN----RIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPE----------RVLPWTLRNRCD 357
            .|:.    .:|.:.|....:|     ||...|. ||:..|:.|          .||.........
Mosquito   333 LWARGAHLSVPWLTGIVPNDG-----FVFSAPI-LKDTDCSKETFAQQKTLLLNVLGGAKETDAL 391

  Fly   358 P-------GQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHG-FVHAMDRLIQSRL--TYGQ 412
            |       |.:..:|:...|            ::.:.|.:||..| ||:.:...::...  |..:
Mosquito   392 PILMERFFGNQSSIGECFTH------------ENVDKLTKLFNEGLFVYPLTLSVRQHANHTGTK 444

  Fly   413 APTYLYRFDFDSPDFNFYRIRFMGKEQR----GVGHVDELGYIFKLPATF-KLDKSRPEFTAIRR 472
            ||.|||||::..|  :.|...|:.....    |:.|.|||.||.:.|..| ...::.|:....:.
Mosquito   445 APIYLYRFNYKGP--HSYSSIFVPDRDELQNFGIVHCDELIYILRAPILFPDFRRNSPDAKVTQV 507

  Fly   473 LVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVL---NISEE---LKFIPQPEMPKLKFFDR 531
            :..:.|.||.|.  .||......|....:.|.:.:.|   |.:||   .|:|...:.....|:.|
Mosquito   508 MTKLIVDFARTG--TAPTGDGDSDRVSDSEFPQALELTNSNSTEEPVLKKYINFYDADMFDFWTR 570

  Fly   532 LY 533
            .|
Mosquito   571 FY 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	178/580 (31%)
LOC4576396	XP_315859.4	None