Protein Alignment alpha-Est4 and Ces2h

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 539
• Identity: 156/539 - (28%)
• Similarity: 228/539 - (42%)
• Gaps: 131/539 - (24%)

  Fly    12 VQTTH-GKVRGIL--LKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCL 73
            ::||| |::.|.|  :|.| |...::|.|||:|.||:|.|||..|...:||.|:||.:...:.||
Mouse    32 IRTTHTGQILGSLIHMKDL-DVGVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCL 95

  Fly    74 Q-VSTLTKEV-----------EGSEDCLYLNISV--KTLNGDPMPVMVYIHGGAFKGG-----DS 119
            | ::.:..:.           ..|||||||||..  ....|..:||||:||||:...|     |.
Mouse    96 QDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYDG 160

  Fly   120 SRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGD 184
            |..|      ..||||.::|.:|||.|||.|..|.  ...||.|..|.:.||||::.|.|.|.|:
Mouse   161 SMLA------AMENVVVVTIQYRLGVLGFFSTGDE--RARGNWGYLDQVAALRWLQQNIAYFGGN 217

  Fly   185 PERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG---FSMELNRLPQMEYRLAKHL-GYEGD 245
            |:|:||||.|:|..:|..|:.||.|:|||..||:.:|   .|..::....:.|:...:| |.|
Mouse   218 PDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALISSLISVSSDVVYQTVANLSGCE-- 280

  Fly   246 NVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFK--PSIESYSTPNAVLLAEPIDLQRTTW 308
            .|||:.|...|:....           |:....|..||  |.|    .....|...|.:|..:..
Mouse   281 QVDSEALVNCLRGKSE-----------EEIMAINKAFKIIPGI----VDGIFLPRHPQELMASAD 330

  Fly   309 SNRIPIILGANSGE-GMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIH-- 370
            .:.:|.|:|.|:.| |..|.|.:.|..|                     ..|..||:.||::.
Mouse   331 FHPVPSIIGVNNDEYGWIIPSSMSMIDS---------------------KKGMDRQMVQAILQRR 374

  Fly   371 -------------------------HFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTY 410
                                     .|.:....|:..|            |...:..|..::...
Mouse   375 ATQMMWPPEVSDLLMEEYMGDNEDPQFLQVQFKEMMKD------------FTFVIPALQVAQFQR 427

  Fly   411 GQAPTYLYRFDFDSPDFNFYRIRFMGKEQRGV--GHVDELGYIFKLPATF----KLDKSRPEFTA 469
            ..||.:.|.|. ..|.|      |...:...|  .|.||:.:||:   :|    ::|.:..|...
Mouse   428 SHAPVFFYEFQ-HRPSF------FKDSKPSHVKADHGDEILFIFR---SFWGGTQVDFTEEEELL 482

  Fly   470 IRRLVAMFVQFAATSDPNA 488
            .||::..:..||...:||:
Mouse   483 SRRMMKYWANFARQRNPNS 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	156/539 (29%)
		Aes	<104..>219	CDD:223730	55/119 (46%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	156/539 (29%)
		Aes	<127..>230	CDD:223730	46/110 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832879
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740