Protein Alignment alpha-Est4 and Aadacl4

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001074717.1
• Gene: Aadacl4 / 435815
• MGIID: 3650257
• Length: 407
• Species: Mus musculus
• Alignment Length: 443
• Identity: 82/443 - (18%)
• Similarity: 146/443 - (32%)
• Gaps: 164/443 - (37%)

  Fly    73 LQVSTLTKEVEGSEDCLYL----NISVKTLNGDPMPV---------------MVYIHGGAFKGGD 118
            :::.::.:.::..:|.:.:    |:.|..::...:||               :::.|||....|.
Mouse    63 MKICSMIRFIQFFQDLIVIKKNHNLVVTNMHFGTIPVRLFQPKAVSSEGRRGIIFYHGGGAICGS 127

  Fly   119 SSRRAWGPDYF--------MKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIR 175
            .       |.:        .:.:.|.:|:|:|         ..||...|..:  ||.:.|.....
Mouse   128 L-------DCYHNLCSFLAQQTDSVVLSVGYR---------KLPDHHYPCIS--KDCLNASIHFL 174

  Fly   176 ANAANFNGDPERITIFGHSSGSMTV----QLLLASPQSEGLFH-RAILLAGFSMELNRLPQMEYR 235
            .|...:..||.|:...|.|.|..||    |.|::.|   .|.| ||.:|...||:     .:.:|
Mouse   175 KNLMTYGVDPSRVVACGESIGGGTVALVTQALVSFP---SLPHIRAQVLITPSMQ-----AINFR 231

  Fly   236 LAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAE- 299
            |..|                                   :|..|:||       .|.:.:.:|.
Mouse   232 LPSH-----------------------------------QQNQNVPF-------LTRDILTIAVC 254

  Fly   300 ---PIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNP-SWLKEFQCNPERVLPWTLRNRCDPGQ 360
               .|||   :|.:              ::|:...|:| :|        |:...|.   ..|...
Mouse   255 KYLDIDL---SWKD--------------ALFNGTYMHPDTW--------EKYRKWL---SSDNIP 291

  Fly   361 RRQLGQALIHHFCEAHGHE--LTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFD 423
            ||...::|:..|.......  |.:.|.:||         .....|:..::.......:|...:.|
Mouse   292 RRFKNKSLLPEFSRPFNEAAFLEIRHNSGL---------EVSPILVDDKIIAQVPEAFLVTCEND 347

  Fly   424 --SPDFNFYRIRFMGKEQRGVG----HVDELGY----------IFKLPATFKL 460
              ..|...|:.|.   |.:||.    ||:: |:          .|..|.:.|:
Mouse   348 PLRDDALLYKKRL---EDQGVPVTWYHVED-GFHGCILLFDKQPFSFPCSIKI 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	82/443 (19%)
Aadacl4	NP_001074717.1	alpha/beta hydrolases	115..380	CDD:473884	74/373 (20%)