DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est4 and Aadacl2fm2

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:NP_001095001.1 Gene:Aadacl2fm2 / 433597 MGIID:3779495 Length:401 Species:Mus musculus


Alignment Length:390 Identity:83/390 - (21%)
Similarity:141/390 - (36%) Gaps:95/390 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 GIRDCSKPLSKCLQVSTLTKEVEGSE----DCLYLNISV-----KTLNGDPMPVMVYIHGGAFKG 116
            |:......||..::|. |||.|....    |..:.:|.|     |..:....|.:::||||||..
Mouse    54 GLMKYEDVLSILVKVQ-LTKPVSDENITVIDTDFSDIPVRLYLPKRKSEKQRPAVIFIHGGAFTL 117

  Fly   117 GDSSRRAWGPDYF-----MKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRA 176
            |......:  ||.     .|.:.|.:.|.:||.|           :.|..|.|:|.:|.:::...
Mouse   118 GSCKMLPY--DYLNRWTANKLDAVVVGIDYRLAP-----------QYPFPAALEDCVLVIKYFLQ 169

  Fly   177 NA--ANFNGDPERITIFGHSSG----SMTVQLLLASPQ-SEGLFHRAILLAGFSMELNRLPQMEY 234
            :.  ..:..||.||.|.|.|.|    :..:|||..:|: .:.:..:|:|..|.......:|  .:
Mouse   170 DTILKKYGVDPTRICISGDSCGGTLATTAIQLLQNNPEHKDKIKAQALLYPGLQFIDTLMP--SH 232

  Fly   235 RLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAE 299
            |:.:|..:....:..::....:..|.||:.:......:.|...|...|                 
Mouse   233 RINEHGPFLSREIAIKLAYLYVTEDTALVQAMQRNEHMPKGSRHLFKF----------------- 280

  Fly   300 PIDLQRTTWSNRIP-------IILGANSGEGMSIFSFVKMNPSWLKEFQCNPERV--LPWTLRNR 355
                  ..||:.:|       :......|: :::| :..:..|.|.....|..::  ||.|....
Mouse   281 ------VNWSDFLPEKYKKNYVYTEPTLGK-LNVF-YPALLDSRLSPLLVNDSQLQSLPLTYILT 337

  Fly   356 C------DPG-----QRRQLGQALIHHFCEAHGHELTVDHTNGLVELFT-----HGFVHAMDRLI 404
            |      |.|     :.|.:|..:.|...|        |..:|.:.|.|     |..|...|:.|
Mouse   338 CEHDILRDDGLIYSTRLRNVGVQVTHDHIE--------DGIHGAILLITVPCNLHLAVRIRDKYI 394

  Fly   405  404
            Mouse   395  394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 83/390 (21%)
Aadacl2fm2NP_001095001.1 Abhydrolase_3 107..372 CDD:400284 63/312 (20%)

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