DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment alpha-Est4 and nceh1a

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:NP_001002303.1 Gene:nceh1a / 432374 ZFINID:ZDB-GENE-040711-2 Length:407 Species:Danio rerio


Alignment Length:303 Identity:52/303 - (17%)
Similarity:102/303 - (33%) Gaps:104/303 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 HDLKPWHGIRDCSKPLSKCLQVSTLTKEVEGSEDCLYLNISVKTL--NGDPMPV---MVYIHGGA 113
            |.|...|.:...:..:.....:..:|.:...:||.|:..:.|:..  .|:...:   :::||||.
Zfish    51 HSLGLSHSVHVINSAIVGFESLVPITNQEIQTEDVLFDGVHVRVYYPQGEEEKLRRAVMFIHGGG 115

  Fly   114 FKGG-------DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVP---------GNA 162
            :..|       ||..|....|.    |.|.:::.:|:.         ||:..|         ...
Zfish   116 WSLGAPKLGSYDSLCRQMSADL----NAVVVTVDYRMA---------PDVHFPVQYEECVQAAKH 167

  Fly   163 GLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELN 227
            .||..:|         ..::.||||:.:.|.|:|.                              
Zfish   168 LLKPEVL---------KQYSVDPERVAVCGDSAGG------------------------------ 193

  Fly   228 RLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPF---------- 282
               .:...:|:.:|.|    :|...:|.|:.....::.|..|.....:|.||:|.          
Zfish   194 ---NLAAAVAQRIGTE----NSTSAKFKLQVLIYPVLQALDFNTASYQQNHNVPILYRRLMARFW 251

  Fly   283 ------KPSI------ESYSTPNAVLLAEPIDLQRTTWSNRIP 313
                  .|.:      .:::..:..||::  :..:..|:|.:|
Zfish   252 LEYLGADPELAHSIMMNNHTAQDQNLLSQ--NRAKLDWTNLLP 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 52/303 (17%)
nceh1aNP_001002303.1 Abhydrolase_3 108..378 CDD:400284 43/246 (17%)

Return to query results.
Submit another query.