Protein Alignment alpha-Est4 and Nlg4

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 154/652 - (23%)
• Similarity: 243/652 - (37%)
• Gaps: 206/652 - (31%)

  Fly    11 VVQTTHGKVRGILLKSLYDEQFY----AFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSK 71
            :|||.:|::.|::| .|...:|.    .|.|:|||.||....||.......||.|||...|....
  Fly    43 IVQTRYGRLHGLIL-PLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPV 106

  Fly    72 CLQ--------VSTLTKEVEG---------------SEDCLYLNISVKT---LNGDPMPVMVYIH 110
            |.|        .:.|.|..:|               ||||||||:....   .|...:||:|:||
  Fly   107 CPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIH 171

  Fly   111 GGAFKGGD------SSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLN-DPDLEV-PGNAGLKDV 167
            |.:|:...      |...::|       .||.:::.:|||.||||:.| :|.... ..|.||.|.
  Fly   172 GESFEWSSGNPYDGSVLASYG-------EVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQ 229

  Fly   168 ILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASP-QSEGLFHRAILLAGFSMELNRLPQ 231
            :.||.||:.|...|.|||..:|:.||.:|:..:..|:.|| ...||||||||::|.:.....|.:
  Fly   230 MAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVE 294

  Fly   232 ----MEYRLAKHLGYE-GDNVD---SQV--------LEFLLKADPALIVSADFFTPLEKRQGHNM 280
                ...:|||.:... .|:::   .|:        ||.|..||   |.:.:|.|
  Fly   295 DPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLAD---IQAPNFLT---------- 346

  Fly   281 PFKPSIESYSTPNAVLLAEP----IDL--------QRTTWSNRIPIILGANSGEGMS-------- 325
            .|.||::.       ::..|    :|:        :|::..:......|...|:|..
  Fly   347 SFGPSVDG-------VVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGG 404

  Fly   326 --------------------------IFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQL 364
                                      :|..|.....|         |.....::|..:..:|.::
  Fly   405 SGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIW---------RFSAHDIQNGFEGERRDKI 460

  Fly   365 GQALIHHFCEAHGHELTVDHTNGLVE----------------------LFTHGFVHAMDRL---- 403
            .:..:.:....|.:|:.....|...:                      .|....|.|.|.|
  Fly   461 IRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANS 525

  Fly   404 ---IQSRLTYGQ------APT-----------YLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDEL 448
               :.|..|.|.      |.|           |.|.||:.:.|.::       .::.|..|.::|
  Fly   526 PPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDY-------PQRMGTVHGEDL 583

  Fly   449 GYIFKLP-----ATFKLDKSRPEFTAIRRLVAMF-VQFAATSDPN--------APLTKSLVDWKP 499
            .|||..|     :.|..:.::.| ||:...|.:| ..||.|.:||        .|::|....::.
  Fly   584 PYIFGAPLVDGFSHFPQNYTKSE-TALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRS 647

  Fly   500 VT 501
            :|
  Fly   648 IT 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	154/652 (24%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	154/652 (24%)