Protein Alignment alpha-Est4 and Nlg3

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 686
• Identity: 153/686 - (22%)
• Similarity: 254/686 - (37%)
• Gaps: 213/686 - (31%)

  Fly    11 VVQTTHGKVRGIL--LKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCL 73
            ::.|.:|.:.|::  |...:.:...|:.|||||.||:|.|||..|.....|.|::...:....|.
  Fly   157 IINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCP 221

  Fly    74 Q--------VSTLTKEVEG---------------SEDCLYLNI---------------------- 93
            |        .:.|.:..:|               |||||||||
  Fly   222 QRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGS 286

  Fly    94 ------------------SVKTLNGDP--MPVMVYIHGGAFKGGD------SSRRAWGPDYFMKE 132
                              |....:|.|  .||:|::||.:::...      |...::|
  Fly   287 SSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYG------- 344

  Fly   133 NVVYISIGHRLGPLGFLSLN-DPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSG 196
            .::.::|.:|||.||||:.| |...::|.|.||.|:|.||.|::.|.|.|.|||..||:.||.:|
  Fly   345 QILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTG 409

  Fly   197 SMTVQLLLAS-PQSEG-LFHRAILLAG-----FSMELNRLPQMEYR--LAKHLGYEGDNVDSQVL 252
            :..|..|::| ...|| ||:||||::|     :|:..|   ..:|.  :|.|:....|...:.::
  Fly   410 AACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSN---PAKYAAIVAHHVNCASDLPHAHLM 471

  Fly   253 EFLLK-----------------------ADPALIVSADFFTPLEKRQGHNMPFKPSIES------ 288
            :.|.:                       .|..:|...|:..|        .|..|:.::
  Fly   472 KCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPP--------APGSPAAQAQAQAST 528

  Fly   289 -----------------YSTPNAVLLAEPIDLQRTTWSN---RIPIILGANSGEGMSIFSFVKMN 333
                             :.||..:   |.|.|.|.|..|   |..::.|....|  :.|||...:
  Fly   529 AAGNGLGGEAGIAAAGGWGTPGQL---ENIVLMRKTAINKLSRYDLMAGVTRAE--AFFSFNSGD 588

  Fly   334 PSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVH 398
            ..:..|.. ...|:|...:||.. .....::...:::.:.:   .|..|.|...:.:       .
  Fly   589 VQYGIEAD-RRSRILKAYVRNTY-TFHLNEIFATIVNEYTD---WERPVQHPINIRD-------E 641

  Fly   399 AMDRLIQSRLTYGQAPT-----------YLYRFDFDSPDFNFYRIRFMGKEQR-GVGHVDELGYI 451
            .::.|..:::....|.|           |||.||        |:.||....|| |..|.::|.||
  Fly   642 TLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFD--------YQTRFGDYPQRQGCIHGEDLPYI 698

  Fly   452 FKLPAT-----FKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTK-----------SLVDWKPV 500
            |..|..     |..:.::.|.:....::..:..|..|.:||..:..           ..::|...
  Fly   699 FGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAY 763

  Fly   501 TRFGKRMVLNISEELKFIPQPEMPKLKFFDRLYEMA 536
            ....|          |::.....||||...|.:.::
  Fly   764 ESVHK----------KYLNFDTKPKLKNHYRAHRLS 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	152/677 (22%)
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	153/686 (22%)