Protein Alignment alpha-Est4 and alpha-Est2

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 225/546 - (41%)
• Similarity: 316/546 - (57%)
• Gaps: 42/546 - (7%)

  Fly    11 VVQTTHGKVRGILLKSLYD-EQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQ 74
            ::.|.:|:|||:..|::|| |.::||:|||||.||:|.|||:.|...:||.|:.:|:...||.:|
  Fly    34 ILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQ 98

  Fly    75 VSTLTKEVEGSEDCLYLNISVKTLNGD-PMPVMVYIHGGAFKGGDSSRRAWGPDYFMKENVVYIS 138
            .:.|...||||||||:||:.||.|..: |:||:|:|:||.|:.|::||..:.||||||:.||:::
  Fly    99 RNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMKKPVVFVA 163

  Fly   139 IGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLL 203
            |.:||..||||||.||.|:|||||||||.::|||||..|.|:|||||..||:.|.|:||.:|.::
  Fly   164 INYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVM 228

  Fly   204 LASPQSEGLFHRAILLAGFSM-ELNRLP--QMEYRLAKHLGYEGDNVDSQVLEFLLK--ADPALI 263
            :.:.|:.||||:||:.:|.:: |....|  ...:|||::|||:||..|:.||.||.|  |.....
  Fly   229 MTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAA 293

  Fly   264 VSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFS 328
            :..|.....|.|......|.|.||.|.|.:.|:.....||....|.|.||:|:|.||.||:..:.
  Fly   294 IDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQ 358

  Fly   329 FVKMNPSWLKEFQCNPERVLPWTLRNRCD-PGQR---RQLGQALIHH-------FCEAHGHELTV 382
            .|:.:|..||.|    ..:||..:|.... .||.   |:|.|...::       ..||
  Fly   359 LVRKDPWALKNF----HNILPREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMFEA------- 412

  Fly   383 DHTNGLVELFTHGFV-HAMDRLIQSRLTYG-QAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHV 445
                  :.:|:|..: |...|.|.:|.:|. :.||||||||||||.||.:|....|...|||.|.
  Fly   413 ------LNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHA 471

  Fly   446 DELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMV-- 508
            |||.|:|......|||||..|:..|.|:|.|:..||::.:||.|...| ..|:.| :..:..|
  Fly   472 DELSYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGS-AKWEAV-QLKENAVEK 534

  Fly   509 -LNISEELKFIPQPEMPKLKFFDRLY 533
             .|||.:|:....||...|..:|..|
  Fly   535 CFNISHDLEMRDLPESDCLAVWDTFY 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	223/540 (41%)
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	223/540 (41%)