Protein Alignment alpha-Est4 and alpha-Est8

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 553
• Identity: 212/553 - (38%)
• Similarity: 323/553 - (58%)
• Gaps: 36/553 - (6%)

  Fly     6 NEDAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLS 70
            :.|..:..|.:|||:|:..:|:|...:|:|:|||:|.||:|.||||.|.:.:.|..::.|:...:
  Fly    29 SNDKVIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRA 93

  Fly    71 KCLQVSTLTKEVEGSEDCLYLNISVKTLNGD-PMPVMVYIHGGAFKGGDSSRRAWGPDYFMKENV 134
            |..||:.:.|:|:|||||||||:..:.|:.. |:||:|:|:||.|:.|::||..:.|||.|.|:|
  Fly    94 KPCQVNIVLKQVQGSEDCLYLNVYTRELHPHRPLPVLVWIYGGGFQMGEASRDLYSPDYIMMEHV 158

  Fly   135 VYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMT 199
            |.:.|.:|||.||||||.|.:|:|||||||||.::||||::.|...|.|||:.||:||.|:|..:
  Fly   159 VLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGAS 223

  Fly   200 VQLLLASPQSEGLFHRAILLAGFSM--------ELNRLPQMEYRLAKHLGYEGDNVDSQVLEFL- 255
            ...::.:.|::||||:.|:::|.::        .:|    ..||||:..||.||..|..:...|
  Fly   224 THYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHIN----WPYRLAQATGYTGDANDRDIFAHLK 284

  Fly   256 -LKADPALIVSADFFTPLEKRQGHNM-PFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGA 318
             .||...|.|:.|..|..|:.|...| .|.|:||.|.||:.|:...|:::.|..|.|.||:::|.
  Fly   285 KCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIGG 349

  Fly   319 NSGEGMSIFSFVKMNPSWLKEF-QCNPERVLPWTLRNRCDPGQRRQLGQAL--IHHFCEAHGHEL 380
            ||.||:.:|..|...|..|.:. .|  |.:.|...  ..|..||:..|:.:  ::......|.:.
  Fly   350 NSFEGLLMFPEVNKWPELLCQLGDC--ENLAPQDA--HVDEQQRKAFGKKVRELYFGDRTPGRKT 410

  Fly   381 TVDHTNGLVELFTHG-FVHAMDRLIQSRLTYGQ-APTYLYRFDFDSPDFNFYRIRFMGKEQRGVG 443
            .::::    :||::. |.|.:.|.:.||..:.. |||:||||||||..||..||...|::.||..
  Fly   411 ILEYS----DLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVRGTC 471

  Fly   444 HVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLT------KSLVDWKPVTR 502
            |.|:|.|:|...|..||.:...||..|:|||:|.|.||.:.|||.|:.      :....|.|:::
  Fly   472 HADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNIPMVCQDEKEQPRGAWLPISK 536

  Fly   503 FGK-RMVLNISEELKFIPQPEMPKLKFFDRLYE 534
            ..| ...||||.::..|..||..||:.:|.:|:
  Fly   537 DDKVFQCLNISHDVHVIDLPEAEKLRLWDCIYD 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	210/544 (39%)
alpha-Est8	NP_524259.2	COesterase	34..564	CDD:395084	209/541 (39%)