Protein Alignment alpha-Est4 and Est-Q

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Alignment Length: 541
• Identity: 145/541 - (26%)
• Similarity: 243/541 - (44%)
• Gaps: 107/541 - (19%)

  Fly     4 DYNEDAPVVQTTHGKVRGILLKSLY----DEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRD 64
            |.:|.|.|....:.....:|....|    |..|..|.|||:|.||:..|||:.|....||.|..:
  Fly    35 DASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLN 99

  Fly    65 CSKPLSKCLQVSTLTKEVEGS--EDCLYLNISVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPD 127
            ......:|..::.|..::..:  ||||.|::..|.|:.. .|||.||:||.|..|.|....  |:
  Fly   100 ALNFGQRCPVITNLDSQMSDAELEDCLTLSVYTKNLSAS-QPVMFYIYGGGFYNGSSEDHP--PN 161

  Fly   128 YFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFG 192
            |.::::||.:...:|:|.||:||....  |:||||.:.|:::||.|::.:.::|.|||:::||||
  Fly   162 YLLEKDVVLVVPQYRVGALGWLSTYTE--ELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFG 224

  Fly   193 HSSGSMTVQLLLASPQS-EGLFHRAILLAG---FSMELNRLPQME-YRLAKHLGYEGDNVDSQVL 252
            .|:|:.....||.||:: :.:|.|||:.:|   .|..:|:.|:.: .|:...||..|.....|::
  Fly   225 QSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQLV 289

  Fly   253 EFLLKA---DPALIVSADFFTPLEKRQGHNMPFKPS--IESYSTPNAVLLAEPIDLQRTTWSNRI 312
            :.:.||   |.....:::.|:|:.......:|.:||  ::||                   ..:|
  Fly   290 KCIQKAKVIDILKATASESFSPIVGDLHGILPQQPSELVKSY-------------------RRQI 335

  Fly   313 PIILGANSGEGMSIFSFV-------------KMNPSWLKEFQ------CNPERVLPWTLRNRC-- 356
            ||:.|....:|    |||             .::...:::|.      .|....|...:.||.
  Fly   336 PILTGFTQHDG----SFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGLTDNILNRLLF 396

  Fly   357 DPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVH------AMDRLIQSRLTYGQAPT 415
            .|       |||     .:|.|...|   :...:|.|:.|:.      |.....|.|.|    |.
  Fly   397 KP-------QAL-----NSHDHSAAV---SSYFDLTTNIFMKSPVITLATKMYTQQRST----PV 442

  Fly   416 YLYRFDFDSP------DFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLV 474
            |:|.|:::..      :|......|.|    ||.|.::..|:|   ||..|:....:.:  :::|
  Fly   443 YVYSFEYEGTYTRFGYEFGNSHYPFNG----GVHHSNDNIYLF---ATHPLEGQDTQMS--QKMV 498

  Fly   475 AMFVQFAATSDPN--APLTKS 493
            .::..||....|.  :||:.:
  Fly   499 DVWTSFAIEGVPRNLSPLSSA 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	143/537 (27%)
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	141/526 (27%)