DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est4 and Nrt

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:NP_476798.1 Gene:Nrt / 39873 FlyBaseID:FBgn0004108 Length:846 Species:Drosophila melanogaster


Alignment Length:396 Identity:111/396 - (28%)
Similarity:166/396 - (41%) Gaps:98/396 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 GKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQV---STL 78
            |.|.|:     .::..:||.|||||.||:..||:| |.:|     |.|.:...:..||.   |.:
  Fly   368 GPVEGV-----KEDGAFAFRGIPYAKPPVDRLRWK-PAEL-----IDDINMCWNDTLQTHNSSVV 421

  Fly    79 TKE------VEGSEDCLYLNISVKTLN-GDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMKENVVY 136
            ..:      ..|.||||||::....:. .:|:||:|.|...:..|...........|....:|::
  Fly   422 CTQRLGNGTTVGDEDCLYLDVVTPHVRYNNPLPVVVLIGAESLAGPSPGILRPSARYSRSHDVIF 486

  Fly   137 ISIGHRLGPLGFLSLNDPDLE----VPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGS 197
            :....|||..|||:|:....|    ..||..|.|:|..|.||:.|..:|.|||:.:|:.||.:|:
  Fly   487 VRPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGA 551

  Fly   198 MTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPAL 262
            ..|.||:.|.:.:||:.||...:|.::    ||      .|.|...|.. :.|::..|..||...
  Fly   552 TLVTLLVNSQKVKGLYTRAWASSGSAI----LP------GKPLSESGKQ-NEQLMATLECADIQC 605

  Fly   263 IVSADFFTPLEKRQGHNMPFKPSIESY--STPNAVLLAEPIDLQRTTWSNRIPIILGANSG---- 321
            :..|                  |.|..  :||: ..|..|:||.:...:|.        ||    
  Fly   606 LREA------------------SSERLWAATPD-TWLHFPVDLPQPQEANA--------SGSRHE 643

  Fly   322 ----EGMSIFSFVKMNPS--WLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHEL 380
                :|..:|.    :||  |.:| |.|.:.||              .:| |..|   |||..:|
  Fly   644 WLVLDGDVVFE----HPSDTWKRE-QANDKPVL--------------VMG-ATAH---EAHTEKL 685

  Fly   381 TVDHTN 386
            ...|.|
  Fly   686 RELHAN 691

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 111/396 (28%)
NrtNP_476798.1 PTZ00121 <3..>222 CDD:173412
alpha/beta hydrolases 362..832 CDD:473884 111/396 (28%)
Blue background indicates that the domain is not in the aligned region.

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