Protein Alignment alpha-Est4 and ces2.3

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001265277.1
• Gene: ces2.3 / 394897
• XenbaseID: XB-GENE-29209066
• Length: 565
• Species: Xenopus tropicalis
• Alignment Length: 602
• Identity: 158/602 - (26%)
• Similarity: 251/602 - (41%)
• Gaps: 148/602 - (24%)

  Fly     7 EDA-PVVQTTHGKVRGILLKSL-YDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPL 69
            ||| |::.|.:|::.|..:.:. .|...:.|.|:|:|.||:|.|||:.|..|:||..:|:.:...
 Frog    29 EDARPLLTTKYGQLLGNTVGAKETDRLVHVFMGVPFAKPPIGLLRFEAPQPLEPWSSVREATAAP 93

  Fly    70 SKCLQ----VSTLTKEVEG-------SEDCLYLNISVKTLNGD--PMPVMVYIHGGAFKGGDSSR 121
            ..|||    :..|.:..:.       ||||||||:......|:  .:||||:||||....|.:|.
 Frog    94 PMCLQDKRGMEDLAEFFKAKFDFPPVSEDCLYLNVFTPADRGENPELPVMVFIHGGGLTMGGASM 158

  Fly   122 RAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPE 186
            .. |......||||.:||.:|||.:||.|..|.  ||.||.|..|.:.||:|:|.|..:|.|:|:
 Frog   159 FE-GTALCAYENVVVVSIQYRLGIMGFFSSGDK--EVRGNFGFLDQVAALQWVRDNIKDFGGNPQ 220

  Fly   187 RITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQV 251
            .:||||.|:|.::|...:.||.|:||||:||..:|.::    ||.:              :.|:.
 Frog   221 SVTIFGESAGGVSVSAQVLSPLSKGLFHKAIAESGVAI----LPGL--------------MTSKN 267

  Fly   252 LEFLLKADPALIVSA--------DFFTPLEKR-QGHNMPFKPSIESYSTP---NAVLLAEPI-DL 303
            .|.|    |.|.|.|        |....|:|: :...:....::.....|   :.|.|.:|. ::
 Frog   268 EEIL----PLLSVVANISSCSVSDLVGCLKKKTEDEIVAITAAMRFVMFPAVVDGVFLPKPAEEI 328

  Fly   304 QRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWL----------------KEFQC---------N 343
            .....||.:|.::|.|:.|.           .|:                |:.|.         .
 Frog   329 LAAKESNPVPFLIGINNHEF-----------GWILPLALNITGYREGMEKKDIQAILGALPLLKT 382

  Fly   344 PERVLPWTLR----NRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLI 404
            ...|:|:.:.    :..||.:.|       ::|.:..|..:               ||....|..
 Frog   383 VSNVIPFIMEEYFGDTNDPKELR-------NNFLDLVGDII---------------FVIPALRTA 425

  Fly   405 QSRLTYGQAPTYLYRFDF------DSPDFNFYRIRFMGKEQRGVGHVDEL-----GYIFKLPATF 458
            :.....| .|.|.|.|..      ||.| :|.:          ..|.|||     |...|....|
 Frog   426 KYHRDSG-LPVYFYEFQHRPSMFADSKD-DFVK----------ADHGDELYFVVGGPFLKSGILF 478

  Fly   459 KLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEELKFIPQPEM 523
            |.:.:..|....:.::..:..||...|||.   ..|.:|.........:.:|:::  |...:.:.
 Frog   479 KSNGTEEEKILSKTIMKYWANFARNGDPNG---LGLAEWPKYDEDEDYLEINLTQ--KSSQRLKG 538

  Fly   524 PKLKFF-----DRLYEM 535
            .:|||:     |::.|:
 Frog   539 GRLKFWTITLPDKIKEL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	154/588 (26%)
ces2.3	NP_001265277.1	COesterase	33..544	CDD:395084	152/585 (26%)