Protein Alignment alpha-Est4 and Est-P

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 144/524 - (27%)
• Similarity: 227/524 - (43%)
• Gaps: 94/524 - (17%)

  Fly     8 DAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLK-PWHGIRDCSKPLSK 71
            |..:|:.|:||:||   |.  :..:|:::.||.|..|.|.|||:.|.... .|..:.:.::...:
  Fly    23 DPLIVEITNGKIRG---KD--NGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVE 82

  Fly    72 CLQVSTLTKE---VEGSEDCLYLNI-SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMKE 132
            |:|.:....|   :.|.||||.::| ..|..|....||:|.:|||||..|..|  .:|.|..|:|
  Fly    83 CMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSGS--IYGHDSIMRE 145

  Fly   133 N---VVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHS 194
            .   ||.||.|  ||||||.|..|..|  |||.||||..|||:||:.|.|:|.|.|:.|.:.|||
  Fly   146 GTLLVVKISFG--LGPLGFASTGDRHL--PGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHS 206

  Fly   195 SGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQ----MEYRLAKHLGYEGDNVDSQVLEFL 255
            :|..:..|.|.....:.|...||.::|.:::...:.|    ..:.|.:.:|....||.:: |:..
  Fly   207 AGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRIVGCGHTNVSAE-LKDC 270

  Fly   256 LKADPAL-IVSA--DF----FTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIP 313
            ||:.||. ||||  .|    :.|..       .|.|.:|....|:|.|..:|..:.::....::|
  Fly   271 LKSKPASDIVSAVRSFLVFSYVPFS-------AFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVP 328

  Fly   314 -IILGANSGEGMSIFSFVKMN----PSWLKEFQCNPERVLPW------------TLRNRCDPGQR 361
             .:.......|.:....::.|    .||:....   :|...|            |:::..|
  Fly   329 WAVTYTTEDGGYNAAQLLERNKLTGESWIDLLN---DRWFDWAPYLLFYRDAKKTIKDMDD---- 386

  Fly   362 RQLGQALIHHFCEAHGHELTVDHTNGLVELFTHG-FVHAMDRLIQSRLTYGQAPTYLYRFDFDSP 425
              |...|...:..  ....:|:....:..:||.. |.:::...|.....||::|  :|.|.:|:|
  Fly   387 --LSFDLRQQYLA--DRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSP--VYSFVYDNP 445

  Fly   426 -------------DFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMF 477
                         |.:|           |..|.|:...||. .|.::......|....::.:.|.
  Fly   446 TDSGVGQLLSNRTDVHF-----------GTVHGDDFFLIFN-TAAYRTGIRPDEEVISKKFIGML 498

  Fly   478 VQFA 481
            ..||
  Fly   499 EDFA 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	144/524 (27%)
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	143/521 (27%)