Protein Alignment alpha-Est4 and Est-6

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 157/548 - (28%)
• Similarity: 241/548 - (43%)
• Gaps: 111/548 - (20%)

  Fly     7 EDAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLK-PWHGIRDCSKPLS 70
            :|..:||...||:||     ..:..:|:::.||||.||.|.|||:.|...| .|..|.|.:|...
  Fly    25 DDPLLVQLPQGKLRG-----RDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPV 84

  Fly    71 KCLQVSTLT---KEVEGSEDCLYLNI-SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAW--GPDYF 129
            .|||....|   .::.|.||||.::: ..|....:..||:.:||||||..|    .||  |.:..
  Fly    85 ACLQWDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFG----AAWQNGHENV 145

  Fly   130 MKE-NVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGH 193
            |:| ..:.:.|.:|||||||:|..|.||  |||.||||..|||:||:.|.|:|.|:|:.:.:.||
  Fly   146 MREGKFILVKISYRLGPLGFVSTGDRDL--PGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGH 208

  Fly   194 SSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYE-GDNV------DSQV 251
            |:|..:|.|.:.......|...|...:|.:::    |.:..:.|:...:| |.||      ||..
  Fly   209 SAGGASVHLQMLREDFGQLARAAFSFSGNALD----PWVIQKGARGRAFELGRNVGCESAEDSTS 269

  Fly   252 LEFLLKADPA----------LIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRT 306
            |:..||:.||          ||.|   :.|.       .||.|.:|....|:|::..:|.|:.::
  Fly   270 LKKCLKSKPASELVTAVRKFLIFS---YVPF-------APFSPVLEPSDAPDAIITQDPRDVIKS 324

  Fly   307 TWSNRIPIIL-------GANSG----EGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQ 360
            ....::|..:       |.|:.    |..|......:|..||:        :.|:.|..|....:
  Fly   325 GKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLE--------LAPYLLFYRDTKTK 381

  Fly   361 R------RQLGQALIHHFCEAHGHELTVDHTNGLVELFTH-GFVHAMDRLIQSRLTYGQAPTYLY 418
            :      |::.|..|.:      ....::..:.|..|||. .|.::....:.....||::|.|.|
  Fly   382 KDMDDYSRKIKQEYIGN------QRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAY 440

  Fly   419 RFD-----------FDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLD-KSRPEFTAI- 470
            .:|           .:..|::|           |..|.|:...||:   .|..| :.||:...|
  Fly   441 VYDNPAEKGIAQVLANRTDYDF-----------GTVHGDDYFLIFE---NFVRDVEMRPDEQIIS 491

  Fly   471 RRLVAMFVQFAATSDPNAPLTKSLVDWK 498
            |..:.|...||  |..|..|.....|:|
  Fly   492 RNFINMLADFA--SSDNGSLKYGECDFK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	157/547 (29%)
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	156/544 (29%)