Protein Alignment alpha-Est4 and CG12869

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 153/593 - (25%)
• Similarity: 229/593 - (38%)
• Gaps: 145/593 - (24%)

  Fly    13 QTTHGKV-RGIL--LKSLYD---EQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSK 71
            |.||.|: :|.|  ||...|   ...|||.|||||..|:..|||.   ..||       |...::
  Fly    27 QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFA---PAKP-------SSSFNR 81

  Fly    72 CLQVST--------------------LTKEVEGSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAF 114
            .||.:|                    :.:.|...||||||||  ....:....:|::|.:.|..|
  Fly    82 TLQATTMQPLCPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEF 146

  Fly   115 KGGDSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAA 179
            .......|..|.| ...|.:|.:|:.:|....|:|||.:....||||.||.||.:||||||.||.
  Fly   147 AYDWPRNRINGLD-LAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNAD 210

  Fly   180 NFNGDPERITIFGHSSG-------------SMTVQLLLASP----QSEGLFHRAILLAGFSMELN 227
            .|.|:|:.||:.||.||             |...||:|.||    ::.|..|:.     :.:|..
  Fly   211 AFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQK-----WIVETG 270

  Fly   228 RLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTP 292
            ::      |.:.||.:.:....:.|...|:...    ..|.....|....|.        :.|:.
  Fly   271 QV------LVQKLGCQFEEAQRRQLMGCLRRKS----REDLLRAYESVYNHG--------NGSSQ 317

  Fly   293 NAVLLAEPIDLQRTTWSNRI-PIILGANSGEGMSIFSFVKMNPSWL---KEFQCNPERVLPWTLR 353
            ..|:|.|.:.|::...:..: |::||..|.||..:..:      ||   :|.|....:.:..||.
  Fly   318 LGVILPEGLPLEQRLRNKTLPPVLLGITSNEGAFLQDY------WLDVAREGQVALHKYINHTLL 376

  Fly   354 NRCDPGQRRQLGQALIHHFCEAHGHELTVD-------HTNGLVELFTHGFVHAMDRLIQS---RL 408
                |...|.|         |:.|.|.:..       :.||..|..:| .:..|.||:..   .|
  Fly   377 ----PNVMRAL---------ESVGEESSTQLAAIRWRYFNGKGEGVSH-LLAGMQRLLSESLYEL 427

  Fly   409 TYGQ-------APTYLYRFDFD-SPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRP 465
            .|.:       ..:|.|.||.. |.|....|..|     .|..|..:|..:.. |:.|: ..:|.
  Fly   428 PYSRILELLNGTTSYAYVFDHSHSMDMRGRRNLF-----GGASHSSDLPLLLG-PSLFQ-QIARR 485

  Fly   466 EFTA-----IRRLVAMFVQFAATSDPNAPLTKSLV--DWKPVTRFGKRMVLNISEELK-----FI 518
            .|:.     .|::...|..|....:|    |...:  .|.|..: ....|.::.|:.|     .:
  Fly   486 RFSGEEEQLCRKIRGAFANFIKNGNP----TPGRIYDGWLPYNK-ENPFVYSLGEQAKTPQTGSV 545

  Fly   519 PQPEMPKL 526
            .:.|:.||
  Fly   546 DEAEVDKL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	153/593 (26%)
		Aes	<104..>219	CDD:223730	48/131 (37%)
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	150/579 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900