Protein Alignment alpha-Est4 and AADACL4

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001013652.1
• Gene: AADACL4 / 343066
• HGNCID: 32038
• Length: 407
• Species: Homo sapiens
• Alignment Length: 107
• Identity: 27/107 - (25%)
• Similarity: 44/107 - (41%)
• Gaps: 14/107 - (13%)

  Fly    96 KTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMKE-NVVYISIGHRLGPLGFLSLNDPDLEVP 159
            |..:..|...:::.||||...|.........:|..:| ..|.:.||:|         ..||...|
Human   105 KAASSRPRRGIIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR---------KLPDHHSP 160

  Fly   160 GNAGLKDVILA-LRWIRANAANFNGDPERITIFGHSSGSMTV 200
              |..:|.:.| :.:::| ...:..||.|:.:.|.|.|...|
Human   161 --ALFQDCMNASIHFLKA-LETYGVDPSRVVVCGESVGGAAV 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	27/107 (25%)
AADACL4	NP_001013652.1	alpha/beta hydrolases	115..378	CDD:473884	25/97 (26%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	119..121		1/1 (100%)