Protein Alignment alpha-Est4 and Nlg3

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 671
• Identity: 157/671 - (23%)
• Similarity: 248/671 - (36%)
• Gaps: 208/671 - (30%)

  Fly     2 SDDYNE------DAPVVQTTHGKVRGIL--LKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKP 58
            |.|.||      .:.:|.|.:|.|.|.:  |...:.:...||.|:|||.||:|.|||..|.....
Mosquito    50 SMDENETLKKSTSSRIVHTKYGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGAL 114

  Fly    59 WHGIRDCSKPLSKCLQ--------VSTLTKEVEG---------------SEDCLYLNISVKTLNG 100
            |.|::...:....|.|        .:.|.:...|               |||||||||.|.|..|
Mosquito   115 WSGVKKADRFSPVCPQRLPDIYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLNIYVPTQAG 179

  Fly   101 -------DPMPVMVYIHGGAFKGGD------SSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLN 152
                   ....|:|::||.:::...      |...::|       .::.::|.:|||.||||:.|
Mosquito   180 SRESSSTSKYAVVVFVHGESYEWNSGNPYDGSVLASYG-------QILVVTINYRLGILGFLNAN 237

  Fly   153 -DPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQ-SEG-LFH 214
             |...:.|.|.||.|:|.||.||:.|...|.|||:.:|:.||.:|:..|..|:||.. .|| |||
Mosquito   238 VDRFSKAPANYGLMDIIAALHWIQENIEAFGGDPKSVTLAGHGTGAACVHFLIASAAVPEGLLFH 302

  Fly   215 RAILLAG------------------FSMELNRLPQMEYRL-------------------AKHLGY 242
            |||:::|                  .|..:|..|.:.::|                   |...|.
Mosquito   303 RAIMMSGSGLAPWSLVGEPAKFAAYVSHHVNCSPDLPHQLLLKCLRDKPLEDILSTSVRAPDFGN 367

  Fly   243 E-GDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAV--LLAEPIDLQ 304
            . |.:||..|:      |...|...| .|......|:....|||...::|.|.:  :|...:.:.
Mosquito   368 AFGPSVDGVVI------DTGEIQQMD-GTHYSDYSGNPAATKPSAHIHNTLNTINAILLRKLAIN 425

  Fly   305 RTTWSNRIPIILGANSGEG--------------------------MSIFSF---------VKMNP 334
            :.   ::..:::|....|.                          .|.:||         |....
Mosquito   426 KL---SKYDLLVGVTRAEAYFAFNSEDVQYGIEADRRAKILKNYVRSTYSFHLNEILATIVNEYT 487

  Fly   335 SWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHA 399
            .|.:..| :|..:...||....|   .|.:..|:  ...:.|    :.||.|
Mosquito   488 DWERPVQ-HPINIRDETLEALSD---ARIVAPAV--QTADLH----SADHRN------------- 529

  Fly   400 MDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPAT-----FK 459
                           ::||.||:.:...:|       .:::|..|.::|.|:|..|..     |.
Mosquito   530 ---------------SFLYVFDYQTKFGDF-------PQRQGCIHGEDLPYLFGAPLVGGFNHFT 572

  Fly   460 LDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLV---------DWKPVTRFGKRMVLNISEEL 515
            .:.::.|......::..:..|..|.:||..|....|         :|.|.....|: .||:..:
Mosquito   573 RNYTKSEIALSEAVMIYWSNFIRTGNPNEQLENDHVRDRTRFKNIEWTPYESVHKK-YLNLDTK- 635

  Fly   516 KFIPQPEMPKLKFFDRLYEMA 536
                    ||||...|.:.::
Mosquito   636 --------PKLKNHYRAHRLS 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	152/650 (23%)
Nlg3	XP_061500330.1	None