DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est4 and Aadacl4

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:XP_233640.4 Gene:Aadacl4 / 313688 RGDID:1565761 Length:407 Species:Rattus norvegicus


Alignment Length:392 Identity:77/392 - (19%)
Similarity:129/392 - (32%) Gaps:140/392 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   105 VMVYIHGGAFKGGDSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVIL 169
            ::.|..|||..|...|..........:.:.|.:|:|:|         ..||...|  ...||.:.
  Rat   115 IIFYHGGGALCGSLDSYHNLCSFLAQQTDSVVLSVGYR---------KLPDHSHP--CITKDCLN 168

  Fly   170 ALRWIRANAANFNGDPERITIFGHSSG----SMTVQLLLASPQSEGLFHRA-ILLAGFSMELNRL 229
            |..:...|...:..||.|:...|.|.|    ::.:|.||:.|....:  || :|:......:|  
  Rat   169 ASIYFMKNLMTYGVDPSRVVACGESIGGGAVALVIQALLSFPSLPRI--RAQVLITPVMQAVN-- 229

  Fly   230 PQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNA 294
                :||..|                                   :|..|:||        ..|.
  Rat   230 ----FRLPSH-----------------------------------QQNQNVPF--------LTND 247

  Fly   295 VLL---AEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRC 356
            :|:   .:.:|:. .:|.:.:      .:|..|.:.|:.|.: .||..                 
  Rat   248 ILMIAVCKYMDID-FSWKDAL------LNGTYMPLDSWKKYS-KWLSS----------------- 287

  Fly   357 DPGQRRQLGQALIHHFCEAHG--------HELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQA 413
            |...||...::|:..|.....        |.|..:.:..|||          |::|      .|.
  Rat   288 DNIPRRFKSKSLLPEFSGPFNETAYLEIKHILDTEVSPLLVE----------DKII------AQL 336

  Fly   414 P-TYLYRFDFD--SPDFNFYRIRFMGKEQRGVG----HVDELGY----------IFKLPATFKLD 461
            | .:|...:.|  ..|...|:.|.   |.:||.    ||:: |:          :|..|.:.|:.
  Rat   337 PQAFLVTCENDPLRDDALLYKKRL---EDQGVPVTWYHVED-GFHGCIFLFDTHLFSFPCSIKIA 397

  Fly   462 KS 463
            |:
  Rat   398 KA 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 77/392 (20%)
Aadacl4XP_233640.4 alpha/beta hydrolases 115..380 CDD:473884 73/371 (20%)

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