Protein Alignment alpha-Est4 and Ces5a

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 149/532 - (28%)
• Similarity: 220/532 - (41%)
• Gaps: 125/532 - (23%)

  Fly    12 VQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQ-- 74
            ||.....|.|.|      |....|.|||:|.||||.|||..|....|||.:|:.:...:.|.|
  Rat    40 VQGKQATVLGRL------EPVNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQNL 98

  Fly    75 -----VSTLTK----EVEGSEDCLYLNISVKTL--NGDPMPVMVYIHGGAFKGGDSSRRAWGPDY 128
                 ...|.|    ::..|||||||||.....  :|..:|||::|.||.|:.|.:|... |...
  Rat    99 EWLFIYQNLLKVHYPKLGVSEDCLYLNIYAPAYANDGSRLPVMMWIPGGGFETGSASIFD-GSAL 162

  Fly   129 FMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGH 193
            ...|:|:.::|.:|||..||  .|..:...|||...:|.:.||:|:|.|...|.|:|:.:||||.
  Rat   163 AAYEDVLIVTIQYRLGIFGF--FNTQNQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGG 225

  Fly   194 SSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGD----NV-DSQVLE 253
            |:|::::..|:.||.|.|||||||:.:|.:: :..|...:..|...|....|    || ||:||.
  Rat   226 SAGAISISSLILSPLSAGLFHRAIMQSGVAI-IPSLKNFDDELKHGLQVVADVCKCNVSDSKVLL 289

  Fly   254 FLLKADPAL--------------IVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQ 304
            ..|:...:|              :|...||.                           .||::|.
  Rat   290 KCLREKSSLELLSLGQKTKAFTRVVDGSFFP---------------------------EEPMELL 327

  Fly   305 RTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCN---PERVLPWTLRNRCDPGQRRQLGQ 366
            .......:|.|:|.|:.|                   |.   |.|..|..|.     |.......
  Rat   328 SQKTFKTVPSIIGVNNQE-------------------CGYILPMREAPEILF-----GSNESTAL 368

  Fly   367 ALIH---HFCEAHGHELTVDHTNG----------LVELFTHGFVHAMDRLIQSRLTYGQA--PTY 416
            .|||   |....:.|.:..|:.:|          |::||...| ..:..|:.:| .:..|  |.|
  Rat   369 TLIHVLLHIPPQYMHIVAKDYFHGKHSLTDIRDTLLDLFGDVF-FVVPGLVTAR-NHRDAGGPVY 431

  Fly   417 LYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLP------ATFKLDKSRPEFTAIRRLVA 475
            .|.|......|...|..|:..:     |.||:.::|..|      ..|: :.:..|....|::::
  Rat   432 FYEFQHRPNCFQNTRPAFVKAD-----HTDEIRFVFGGPFLEGDVVMFE-EATEDEKLLSRKMMS 490

  Fly   476 MFVQFAATSDPN 487
            .:..||.:.|||
  Rat   491 YWANFARSGDPN 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	149/532 (28%)
Ces5a	NP_001012056.2	COesterase	29..539	CDD:395084	149/532 (28%)