DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment alpha-Est4 and Aadacl2fm3

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:NP_001099906.1 Gene:Aadacl2fm3 / 295072 RGDID:1560324 Length:401 Species:Rattus norvegicus


Alignment Length:429 Identity:100/429 - (23%)
Similarity:151/429 - (35%) Gaps:154/429 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 LGTLRFKEPHDLKPWHGIRDCSKPLSKCLQVSTLTKEVEGSEDCLYLNISV--KTLNGDPM---- 103
            :|.::|:|...:  ..||:|              ||.|...      ||:|  ...|..|:    
  Rat    53 MGLMKFEEFFGI--LMGIQD--------------TKAVSDE------NITVIDTDFNDIPVRLYL 95

  Fly   104 ---------PVMVYIHGGAFKGG-------DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLN 152
                     |.::|||||||..|       ||..| |..:   |.:.|.|:..:||.|.....  
  Rat    96 PKRESERKRPAVIYIHGGAFILGSFKMLPYDSMNR-WTAN---KLDAVVIAPDYRLAPQYLFP-- 154

  Fly   153 DPDLEVPGNAGLKDVILALRWIRAN--AANFNGDPERITIFGHSSG----SMTVQLLLASPQSEG 211
                     |.|:|.:|..::...:  .|.:..||.||.|.|.|||    :...|||...|:.:.
  Rat   155 ---------AALEDCVLVTKFFLQDKVLAKYRVDPTRICISGDSSGGTLAATVTQLLQDDPEYKN 210

  Fly   212 LFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQ 276
            ......||                      |.|    .|.|:.|:   |:.            |:
  Rat   211 KIRAQTLL----------------------YPG----LQALDTLM---PSF------------RE 234

  Fly   277 GHNMPF---KPSIESYSTPNAVLLAEPIDLQRTTWSN-RIPIILGANSGEGMSIFSFVKMN---P 334
            ..:.||   |.:|:.    ..:.|:|..:|.:|...| .:|       .|...:|.||..:   |
  Rat   235 YEHGPFLTRKVAIKM----TCLYLSEDKELPKTILRNAHVP-------KESRHLFKFVNWSDFLP 288

  Fly   335 SWLKEFQCNPERVL-------PWTLRNRCDP-----GQRRQLGQALIHHFCEAHGHELTVDHTNG 387
            ...|:.....|.||       |..:.:|..|     .|.::|....| ..||   |::..|  :|
  Rat   289 EKYKKNHVYTEPVLGKLSASHPGLVDSRVSPLLVNDSQLQKLPLTYI-LTCE---HDILRD--DG 347

  Fly   388 LVEL---------FTHGFVHAMDRLIQSRLTYGQAPTYL 417
            |:.:         |||.  |..|. |...:::..||.:|
  Rat   348 LIYVTRLRNVGVTFTHD--HIEDG-IHGAVSFATAPFHL 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 100/429 (23%)
Aadacl2fm3NP_001099906.1 Abhydrolase_3 107..372 CDD:400284 82/340 (24%)

Return to query results.
Submit another query.