Protein Alignment alpha-Est4 and Ces2i

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_008758816.2
• Gene: Ces2i / 292152
• RGDID: 1565045
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 161/591 - (27%)
• Similarity: 249/591 - (42%)
• Gaps: 133/591 - (22%)

  Fly     9 APVVQTTHGKVRGILL-----KSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKP 68
            :|:..|..|:|||..:     ||    ..:.|.|||:|.||:|.|.|..|.|.:||.|:||.:..
  Rat    31 SPIRNTQTGQVRGSFVHVKDTKS----GVHTFLGIPFAKPPVGPLHFAPPEDPEPWSGVRDGTSQ 91

  Fly    69 LSKCLQVSTL----TKEVE-------GSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKGGDSS 120
            ...|||...:    .||::       .|||||||||  ......|..:||||:||||....|.:|
  Rat    92 PDMCLQTDIMKEDFIKEMKLTMHPTPMSEDCLYLNIYTPAHAREGSNLPVMVWIHGGGLVLGSAS 156

  Fly   121 RRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDP 185
            ... .......|.:|.::|.:|||.|||.|..|.  ...||.|..|.:.||.|::.|.|.|.|:.
  Rat   157 MNV-ASTLAATEEIVIVAIQYRLGILGFFSTGDE--HARGNWGYLDQVAALCWVQQNIAYFGGNH 218

  Fly   186 ERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLP-------QMEYRLAKHL-GY 242
            .::||||.|:|..:|...:.||.|:||||.||:.:|.::    ||       ::.|:...:| |.
  Rat   219 GKVTIFGVSAGGTSVSSHVVSPMSKGLFHGAIMQSGVAL----LPDLISDTSEVVYKTVANLSGC 279

  Fly   243 EGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFK--PSIESYSTPNAVLLAEPIDLQR 305
            |..  ||:.|...|:|.....:.|           .|..||  |.:    .....|...|.:|..
  Rat   280 EAS--DSEALIRCLRAKSKQEILA-----------INQVFKMIPGV----VDGKFLPKHPQELLA 327

  Fly   306 TTWSNRIPIILGANSGE-GMSIFSFVKMN-----------PSWLK----EFQCNPE---RVLPWT 351
            :...:.:|.|:|.|:.| |:.:..|:.::           |:.||    :....||   .::...
  Rat   328 SGDFHPVPSIIGVNTDECGLGVPMFMGLDHIIKKITRDTLPTVLKSTAAQMMLPPECIDLIMEEY 392

  Fly   352 LRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTY 416
            :.:..||       :.|...|.|..|                 .|:..:..|..:.....|||.|
  Rat   393 MGDTEDP-------ETLQEQFKEMLG-----------------DFMFVIPALEVAHFQRSQAPVY 433

  Fly   417 LYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATF---KLDKSRPEFTAIRRLVAMFV 478
            .|.|. ..|.|    |:.:........|.|::.::|.  :.|   ..|.:..|....||::..:.
  Rat   434 FYEFQ-HLPSF----IKQVRPSHVKADHGDDILFVFS--SYFWGMNFDITEEEELLKRRVMKYWA 491

  Fly   479 QFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEE-LKFIPQP------EMPKLKFF-----DR 531
            .||...:||   ::.|..|.         ||:.:|: |:...||      :..:|:|:     .:
  Rat   492 NFARNGNPN---SEDLPYWP---------VLDHNEQYLQLNTQPAVGRALKARRLQFWTKTLPQK 544

  Fly   532 LYEMAG 537
            :.|:.|
  Rat   545 IQELKG 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	158/576 (27%)
Ces2i	XP_008758816.2	COesterase	30..537	CDD:395084	158/576 (27%)