Protein Alignment alpha-Est4 and Ces2g

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001099645.1
• Gene: Ces2g / 291952
• RGDID: 1308358
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 569
• Identity: 161/569 - (28%)
• Similarity: 250/569 - (43%)
• Gaps: 102/569 - (17%)

  Fly     7 EDAPVVQTTHGKVRGILLKSL-YDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLS 70
            |.:|:..|..|:|:|.|..|. :....:.|.|||:|..|:|.|||..|...:||.|:||.:...:
  Rat    31 ESSPIRNTHTGQVQGKLTHSKDFKSGVHTFLGIPFAKAPVGPLRFAPPEAPEPWSGVRDGTSQSN 95

  Fly    71 KCLQVSTLTKE-----------VEGSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKGG----- 117
            .|.|...:..|           |..|||||||||  ......|..:||||:|||||...|
  Rat    96 ICPQNVRMNMEGLKEMKLTLPPVSMSEDCLYLNIYAPAHAHEGSHLPVMVWIHGGALTVGMASMY 160

  Fly   118 DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFN 182
            |.|..|      ..|:||.::|.:|||.|||.|..|.  ...||.|..|.:.||||::.|.|:|.
  Rat   161 DGSMLA------ATEDVVVVTIQYRLGVLGFFSTGDH--HARGNWGYLDQVAALRWVQQNIAHFG 217

  Fly   183 GDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSM---ELNRLPQMEYRLAKHL-GYE 243
            |:|:.:||||.|:|.::|...:.||.|:|||||||:.:|.::   .:....:|.|::...| |.|
  Rat   218 GNPDCVTIFGESAGGLSVSSHVVSPMSKGLFHRAIMESGVALMPGTIFNFSEMVYQMVVKLSGCE 282

  Fly   244 GDNVDSQVLEFLLKA---DPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQR 305
            .  :|.:.|...|:.   :...::|.:|           ......::....||     .|.:|..
  Rat   283 A--MDPESLVHCLRGKSEEQITVISKEF-----------QMIPAVVDGEFLPN-----HPQELLA 329

  Fly   306 TTWSNRIPIILGANS-----------GEGMSIFSFVKMN-PSWLKEFQCNPERVLPWTLRNRC-D 357
            :...:.:|.|:|.|:           |...:|....:.| .::||:  ..|:.:||    ..| |
  Rat   330 SADFHPVPSIIGFNNDEYGWIVPKVIGSAQTIKGITRENLQAFLKD--TAPQMMLP----PECSD 388

  Fly   358 PGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDF 422
            ......:|........:|...|:..|            |:..:..|..:|.....||.|.|.|..
  Rat   389 LLMEEYMGDIEDPQTLQAQFTEMMED------------FMFVIPSLQVARFQRSHAPVYFYEFQH 441

  Fly   423 DSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATF----KLDKSRPEFTAIRRLVAMFVQFAAT 483
            .|......|...:..:     |.||:.::|   .:|    ||:.:..|....||::..:..||..
  Rat   442 QSSFLKDIRPPHVKAD-----HGDEVPFVF---GSFFWGMKLNLTEGEKLLNRRMMKYWANFARY 498

  Fly   484 SDPNAPLTKSLVDWKPVTRFGKR-MVLNISEELKFIPQPEMPKLKFFDR 531
            .:||   :.||..| ||..:.:: :.||....:..|.:..  ||:|:.:
  Rat   499 GNPN---SNSLPYW-PVFDYDEQYLQLNTQPAVGRIQKAR--KLQFWTK 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	159/564 (28%)
Ces2g	NP_001099645.1	COesterase	32..539	CDD:395084	159/564 (28%)