Protein Alignment alpha-Est4 and cest-9.2

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 140/548 - (25%)
• Similarity: 212/548 - (38%)
• Gaps: 158/548 - (28%)

  Fly    11 VVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQV 75
            |::|::|:||||...|..:...|.|..:|:|.||:|.|||..|.....|.|:.|.||....||..
 Worm    23 VIETSYGRVRGITEWSDDNNHKYMFKSVPFAKPPIGKLRFAPPQYPDSWSGVLDASKYSPACLSN 87

  Fly    76 S--TLTKEVEGSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYF-----MK 131
            |  |.|.:...||||||:||  |.|.|. ....|:||.||||: .|||:  ...||.|     :.
 Worm    88 SSTTSTPQEHVSEDCLYINIFTSEKCLR-SKCAVIVYFHGGAY-NGDSA--TMFPDNFILERYVA 148

  Fly   132 ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSG 196
            |:|:....|.|||..|.|... |...:..|..:.|.:.||.::.....||.|||:::||.|||||
 Worm   149 EDVILAIPGVRLGVFGQLYFG-PSALLTENLFMFDAVQALDFVHNEIPNFGGDPKQVTIMGHSSG 212

  Fly   197 SMTVQLLLASPQSE---GLFHRAILLAGFSM--ELNRLPQMEYRLAKHLG-YEGDNVD------S 249
            ...|:.|..|...:   .||.:.|:|:|..|  ..:.|....:.:::.|| :.|...:      :
 Worm   213 GTLVEALGFSNSVDPDLKLFQQIIVLSGTGMFGFYDLLVDNSFIISEKLGCFNGTQEERTDANIA 277

  Fly   250 QVLEFLLKAD-------------------PALIVSADFFT---PLEKRQGHNMP----------- 281
            ::||.:.:.|                   .:|:..|.|..   .:||.:....|
 Worm   278 EILECMRQIDGHEIVGMQKHMEDVYKLTFKSLLRGAPFMELNGKIEKFRNSTSPRNAIFGTTEYE 342

  Fly   282 FKPSIESY--------STPNAVLLAEPIDLQRTTWSNRIPIILG----------------ANSGE 322
            |:..:|.|        ...|.|.:|:..|.:  ...|...:|.|                ||:|.
 Worm   343 FRNEVERYLYITTTFLDFENPVAVAQHFDDE--LMQNMDTMINGDAVSIFVSAAAFSSAMANAGA 405

  Fly   323 GMSIFS-----------------------------------FVKMNPSWLKEFQCNPERVLPWTL 352
            .:.:|.                                   :.|:..::.|....:||    |
 Worm   406 DVYLFETRQWPYSFHVSDMQYFIGIHREVLHTHDMDILDSFYSKLLVNFTKTGAPSPE----W-- 464

  Fly   353 RNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYL 417
             |..:|.:...|              ||.||..||...:...|: |  |:.:.  ..||....|
 Worm   465 -NSLEPEKMNYL--------------ELRVDTRNGKGPVMLEGY-H--DKEVS--FWYGDMMDY- 508

  Fly   418 YRFDFDSPDFNFYRIR---FMGKEQRGV 442
                    |.|..::|   .:.:|.:||
 Worm   509 --------DRNITKMRQSKGLPRENQGV 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	140/548 (26%)
		Aes	<104..>219	CDD:223730	44/122 (36%)
cest-9.2	NP_741910.3	Abhydrolase	19..501	CDD:304388	131/510 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157183
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740