Protein Alignment alpha-Est4 and Ces1a

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001013786.2
• Gene: Ces1a / 244595
• MGIID: 3648919
• Length: 563
• Species: Mus musculus
• Alignment Length: 531
• Identity: 152/531 - (28%)
• Similarity: 229/531 - (43%)
• Gaps: 82/531 - (15%)

  Fly    10 PVVQTTHGKVRGILLKSLYDEQFYA-FDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCL 73
            |||.|..|||.|..:......|..| |.|:|:|.||||.|||..|...:.|..:::.:.....|.
Mouse    24 PVVDTLQGKVMGKYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAETWSSVKNTTSYPPMCS 88

  Fly    74 QVS--------TLTKEVEG-----SEDCLYLNISVKT--LNGDPMPVMVYIHGGAFKGGDSSRRA 123
            |::        ..|.::|.     |||||||||...|  .:.|.:||||::|||....|.:|...
Mouse    89 QITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGASTFD 153

  Fly   124 WGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERI 188
             |......||||.:.|.:|||..||||..|....  ||.|..|.:.||:|::.|.|||.|||..:
Mouse   154 -GLALSTHENVVIVVIQYRLGIWGFLSTGDEHSR--GNWGHLDQVAALQWVQNNIANFGGDPSSV 215

  Fly   189 TIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNV---DSQ 250
            |:||.|:|..:|.:|:.||.::.||.|||..:|.::......:...|.|:.:......|   .:.
Mouse   216 TLFGESAGGESVSVLVLSPLTKNLFQRAISESGVALTPCLFRETTRRAAEQVAIATGCVATTSAD 280

  Fly   251 VLEFLL-KADPALIVSA---DFFT------PLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQR 305
            ::..|. |.:..|:.:.   .||.      |.|     :.||..::    ....||...|.::..
Mouse   281 IVHCLREKTEEELLATTLKMKFFALDLLGDPRE-----SYPFLTTV----IDGVVLPKAPEEILA 336

  Fly   306 TTWSNRIPIILGANSGEGMSIFS-FVKMNPSW-LKEFQCNPERV--LPW------TLRNRCDP-G 359
            ....|.:|.|:|.|..|    |. |:.|...: |.|.:.:.:..  |.|      .:.....| .
Mouse   337 EKSFNTVPYIVGINKQE----FGWFIPMMMGYPLSEGKLDQKSATSLLWKSYPLTNISKELTPVA 397

  Fly   360 QRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQ---APTYLYRFD 421
            ..:.||.:    .|.....:|.:|....:  ||      |:..:|.:|  |.:   ||||:|.|.
Mouse   398 TEKYLGGS----DCPDKKKDLFLDMMGDV--LF------AVPSVIVAR--YHRDAGAPTYMYEFK 448

  Fly   422 FDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDP 486
            : .|.|    :..|..:.....|.||:..::..| ..|...|..|......::..:..||...:|
Mouse   449 Y-HPSF----VSDMRPKTVIADHGDEVYSVWGTP-FLKEGASEEEINLSTMMMKFWGNFARNGNP 507

  Fly   487 NAPLTKSLVDW 497
            |.   :.|..|
Mouse   508 NG---EGLPHW 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	152/531 (29%)
		Aes	<104..>219	CDD:223730	51/114 (45%)
Ces1a	NP_001013786.2	Esterase_lipase	25..536	CDD:238191	151/530 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750