Protein Alignment alpha-Est4 and Ces2e

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_766347.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 588
• Identity: 164/588 - (27%)
• Similarity: 254/588 - (43%)
• Gaps: 132/588 - (22%)

  Fly     7 EDAPVVQTTH-GKVRGIL--LKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKP 68
            :.|..::.|| |:|||.|  :|.. |...:.|.|||:|.||:|.|||..|...:||.|:||.:..
Mouse    28 DSASPIRNTHTGQVRGSLVHVKDT-DIAVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSH 91

  Fly    69 LSKCLQ------------VSTLTKEVEGSEDCLYLNISV--KTLNGDPMPVMVYIHGGAFKGG-- 117
            .:.|||            ::.:...:..|||||||||.|  ....|..:||||:|||||...|
Mouse    92 PNMCLQNDNLMGSEDLKMMNLILPPISMSEDCLYLNIYVPAHAHEGSNLPVMVWIHGGALTVGMA 156

  Fly   118 ---DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAA 179
               |.|..|      ..|:||.::|.:|||.|||.|..|.  ...||.|..|.:.||||::.|..
Mouse   157 SMYDGSMLA------ATEDVVVVAIQYRLGVLGFFSTGDQ--HAKGNWGYLDQVAALRWVQQNIV 213

  Fly   180 NFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLP-------QMEYRLA 237
            :|.|:|:|:||||.|:|..:|...:.||.|:||||.||:.:|.::    ||       :|.:|:.
Mouse   214 HFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVAV----LPDLISSSSEMVHRIV 274

  Fly   238 KHL-GYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGH----NMPFK--PSIESYSTPNAV 295
            .:| |...  |:|:.|...|:.               |.:..    |..||  |.:    .....
Mouse   275 ANLSGCAA--VNSETLMCCLRG---------------KNEAEMLAINKVFKIIPGV----VDGEF 318

  Fly   296 LLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRC---- 356
            |...|.:|..:...:.:|.|:|.|:.|...|...: |:|:  ::.:....:.||..|::..
Mouse   319 LPKHPQELMASKDFHPVPSIIGINNDEYGWILPTI-MDPA--QKIEEITRKTLPAVLKSTALKMM 380

  Fly   357 -DPGQRRQLGQALIHHF---------CEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYG 411
             .|    :.|..|:..:         .:|...|:..|            |:..:..|..:.....
Mouse   381 LPP----ECGDLLMEEYMGDTEDPETLQAQFREMKGD------------FMFVIPALQVAHFQRS 429

  Fly   412 QAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDEL----GYIFKLPATFKLDKSRPEFTAIRR 472
            .||.|.|.|......|..:|..::..:     |.||:    ||.|   ...||..:..|....||
Mouse   430 HAPVYFYEFQHRPSFFKDFRPPYVKAD-----HGDEIFLVFGYQF---GNIKLPYTEEEEQLSRR 486

  Fly   473 LVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEEL-------------KFIPQPEMP 524
            ::..:..||...:||   ::.|..|..:....:.:.|:|...:             |.:|| ::.
Mouse   487 IMKYWANFARHGNPN---SEGLPYWPVMDHDEQYLQLDIQPSVGRALKARRLQFWTKTLPQ-KIQ 547

  Fly   525 KLK 527
            :||
Mouse   548 ELK 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	164/587 (28%)
Ces2e	NP_766347.1	COesterase	30..538	CDD:395084	159/571 (28%)