Protein Alignment alpha-Est4 and Aadacl4fm4

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001078973.1
• Gene: Aadacl4fm4 / 230890
• MGIID: 2685282
• Length: 407
• Species: Mus musculus
• Alignment Length: 373
• Identity: 84/373 - (22%)
• Similarity: 129/373 - (34%)
• Gaps: 137/373 - (36%)

  Fly    93 ISVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGP--------DYFMKE-NVVYISIGHRLGPLGF 148
            :|.|...|     :::.||||        .|:|.        .:.::| :.|.:|:|:|..|...
Mouse   107 VSSKLRRG-----IIFYHGGA--------AAFGSLDIYHNLCSFLVRETDSVLLSVGYRKLPKHH 158

  Fly   149 --LSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTV----QLLLASP 207
              .:|||         .|...||.|:.:.    .:..||.|:.:.|.|.|...|    |.|:::|
Mouse   159 HPAALND---------CLSATILFLKALE----TYGVDPSRVVLCGDSFGGWVVASISQTLVSTP 210

  Fly   208 QSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPL 272
            .                    |||:.   |:.|.|.    ..||:.|||   |:|
Mouse   211 S--------------------LPQIR---AQVLIYP----ILQVINFLL---PSL---------- 235

  Fly   273 EKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNP--- 334
              :|..|:|              ||::  ||......|.:.|.|  :.|:.|...:.:.::.
Mouse   236 --QQNKNIP--------------LLSK--DLLIIFVCNYLAIDL--SWGDSMLTGAVIPLDKWKK 280

  Fly   335 --SWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFV 397
              .||..... |.|:  |:     ...|...||     ||.||...|.            .|.|.
Mouse   281 YRKWLSSDNI-PRRL--WS-----QDTQPEFLG-----HFNEAAYLET------------KHIFN 320

  Fly   398 HAMDRLIQSRLTYGQAP-TYLYRFDFD--SPDFNFYRIRFMGKEQRGV 442
            ..:..:|....|..|.| .:|...::|  ..|...|:.|.   |.:||
Mouse   321 PEISPIIADDKTIAQLPEAFLVSCEYDIVRDDTLLYKKRL---EDQGV 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	84/373 (23%)
Aadacl4fm4	NP_001078973.1	alpha/beta hydrolases	115..378	CDD:473884	81/360 (23%)