Protein Alignment alpha-Est4 and Tg

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_006520808.2
• Gene: Tg / 21819
• MGIID: 98733
• Length: 2767
• Species: Mus musculus
• Alignment Length: 541
• Identity: 133/541 - (24%)
• Similarity: 225/541 - (41%)
• Gaps: 119/541 - (21%)

  Fly    10 PVVQT-----------THGKVRG---ILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWH 60
            |:||:           :.|:::|   ::......:|.|.|.|:|||.|||...||:.|..|. |.
Mouse  2188 PLVQSDVTSTPSVRIDSFGQLQGGSQVIKVGTAWKQVYRFLGVPYAAPPLADNRFRAPEVLN-WT 2251

  Fly    61 GIRDCSKPLSKCLQVSTLT-KEVEGSEDCLYLNISVKTLNGDPMPVMVYIH--------GGAFKG 116
            |..|.:||.:.|.|..|.| ...:.:|||||||:.|.........|:|:.|        ||....
Mouse  2252 GSWDATKPRASCWQPGTRTPTPPQINEDCLYLNVFVPENLVSNASVLVFFHNTMEMEGSGGQLTI 2316

  Fly   117 GDSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANF 181
            ..|...|.|       |.:.::..:|||..||||....  ||.||.||.|.:.||.|::::...|
Mouse  2317 DGSILAAVG-------NFIVVTANYRLGVFGFLSSGSD--EVAGNWGLLDQVAALTWVQSHIGAF 2372

  Fly   182 NGDPERITIFGHSSGS--MTVQLLLASPQSEGLFHRAILLAGFSM------ELNRLPQMEYRLAK 238
            .|||:|:|:....||:  .::.||::.|....||.:|:|:.|.::      ...|..|....|||
Mouse  2373 GGDPQRVTLAADRSGADVASIHLLISRPTRLQLFRKALLMGGSALSPAAIISPERAQQQAAALAK 2437

  Fly   239 HLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFK---PSIESY---STPNAVLL 297
            .:|....::  |.:...|:..||.|:: |..|.|....|   ||.   |.::..   ..|:. .|
Mouse  2438 EVGCPTSSI--QEVVSCLRQKPANILN-DAQTKLLAVSG---PFHYWGPVVDGQYLRELPSR-RL 2495

  Fly   298 AEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMN-PSWLKEFQ-----CNPERVLPWTLRNRC 356
            ..|:.:       ::.:::|.:..:|:       :| ...:|:|:     .|.:......|:|..
Mouse  2496 KRPLPV-------KVDLLIGGSQDDGL-------INRAKAVKQFEESQGRTNSKTAFYQALQNSL 2546

  Fly   357 --DPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHA-MDRLI----------QSRL 408
              :....|.|..|:.::         :::|:......|:....:| .|..|          .:|.
Mouse  2547 GGEDSDARILAAAVWYY---------SLEHSTDDYASFSRALENATRDYFIICPMVNMASLWARR 2602

  Fly   409 TYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVD---ELGYIFKLP--ATFKLDKSRPEFT 468
            |.|.  .::|..                .|..|.|.::   ::.|.|.||  :.::...|..|.:
Mouse  2603 TRGN--VFMYHV----------------PESYGHGSLELLADVQYAFGLPFYSAYQGQFSTEEQS 2649

  Fly   469 AIRRLVAMFVQFAATSDPNAP 489
            ...:::..|..|..:.:||.|
Mouse  2650 LSLKVMQYFSNFIRSGNPNYP 2670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	133/541 (25%)
		Aes	<104..>219	CDD:223730	40/124 (32%)
Tg	XP_006520808.2	TY	34..93	CDD:238114
		TY	96..161	CDD:238114
		TY	301..359	CDD:238114
		TY	<612..658	CDD:238114
		TY	661..726	CDD:238114
		TY	730..>776	CDD:381826
		TY	<893..922	CDD:381826
		TY	1005..1074	CDD:238114
		TY	1150..1211	CDD:238114
		Ephrin_rec_like	1464..1509	CDD:311571
		TY	1519..1566	CDD:214561
		COesterase	2198..2717	CDD:365897	130/531 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832913
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930