Protein Alignment alpha-Est4 and Ces2e

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001093947.1
• Gene: Ces2e / 192257
• RGDID: 621563
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 164/581 - (28%)
• Similarity: 253/581 - (43%)
• Gaps: 120/581 - (20%)

  Fly     7 EDAPVVQTTH-GKVRGILL-----KSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDC 65
            :.|..::.|| |:|||..:     ||    ..:.|.|||:|.||:|.|||..|...:||.|:||.
  Rat    28 DSASPIRNTHTGQVRGSFVHVKDTKS----GVHTFLGIPFAKPPIGPLRFAPPEPPEPWSGVRDG 88

  Fly    66 SKPLSKCLQ-VSTLTKE----------VEGSEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKGG 117
            :...:.||| :..|..|          |..|||||||:|  ...|.....:||||:||||....|
  Rat    89 TSHPAMCLQNIDGLNLENLKIKMSRSPVSMSEDCLYLSIYTPAHTHKDSNLPVMVWIHGGGLCWG 153

  Fly   118 -----DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRAN 177
                 |.|..|      ..|:||.::|.:|||.|||.|..|.  ...||.|..|.:.||||::.|
  Rat   154 MASTYDGSMLA------AIEDVVVVTIQYRLGILGFFSTGDE--HARGNWGYLDQVAALRWVQQN 210

  Fly   178 AANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRL---PQMEYRLAKH 239
            ..:|.|:|:|:||||.|:|.::|...:.||.|:||||.||:.:|.::..|.:   .::.|.:..:
  Rat   211 IVHFGGNPDRVTIFGESAGGISVSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIYTMVAN 275

  Fly   240 L-GYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYS--TPNAVLLAEPI 301
            | |.|  .|||:.|...|:               ||.:...:.....:.:.|  .....|...|:
  Rat   276 LSGCE--PVDSEALMSCLR---------------EKSEEEMLAINNIVRTISGVVDGKFLPRHPL 323

  Fly   302 DLQRTTWSNRIPIILGANSGEGMSIFSFV--KMNP-SWLKEFQCNPERVLPWTLRN--------- 354
            :|..:...:.:|.|:|.||.|    :.::  .::| |.:||......|.:   |:|
  Rat   324 ELLASVDFHPVPSIIGINSDE----YGWIIPMLHPDSTMKEINRETMRAV---LKNTAVQMMLPP 381

  Fly   355 RC-DPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLY 418
            .| |......:|........:...:|:..|            |:..:..|..:......||.|.|
  Rat   382 ECSDLLMEEYMGDTEDSKTLQIQFNEMMGD------------FIFVIPALQVAHFQRSHAPVYFY 434

  Fly   419 RFDFDSPDFNFYRIRFMGKEQRGVGHVDEL----GYIFKLPATFKLDKSRPEFTAIRRLVAMFVQ 479
            .|...|   ||  ::.:........|.|||    ||:|   ...|...:..|....|:::..:..
  Rat   435 EFQHQS---NF--LKDIRPPHVKADHGDELPYVIGYLF---WDMKFVFTEEEKLLSRKMIKYWAN 491

  Fly   480 FAATSDPNAPLTKSLVDWKPVTRFGKRMVLNI---------SEELKF----IPQPEMPKLK 527
            ||...:||   ::.|..|..:....:.:.|:|         :..|||    :|| ::.:||
  Rat   492 FARHGNPN---SEGLPYWPALDHDEQYLQLDIQPVVGRALKARRLKFWTKTLPQ-KIQELK 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	164/580 (28%)
Ces2e	NP_001093947.1	COesterase	30..536	CDD:395084	159/564 (28%)