Protein Alignment alpha-Est4 and cest-28

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 147/583 - (25%)
• Similarity: 244/583 - (41%)
• Gaps: 135/583 - (23%)

  Fly    12 VQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQVS 76
            :..|.|.::|.:.: :.|:....:.|||:|.|   .:|||:|.....|..:|||:|...:|.|..
 Worm    17 LNATCGPIQGNVYR-IGDKTVDGYLGIPFAKP---LVRFKKPEPAGTWEEVRDCTKYGPRCPQSG 77

  Fly    77 TLTKEVEGSED-------CLYLNISVKTLN----GDPMPVMVYIHGGAFKGGDSSRRAWGPDYFM 130
            ...:.:...:|       ||.||:..|..:    ....|||||||||.::...|....   ||.:
 Worm    78 PFAEAINFQKDDIPDEANCLTLNVFSKISDSKNFNKTRPVMVYIHGGGYECSASRDYC---DYSV 139

  Fly   131 K-----ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITI 190
            .     ::||.:::.:|:|.|||.:..  |...|||..|.|:.|.|.||:.:..:|.|||..|||
 Worm   140 AGTLPLKDVVVVTLNYRVGILGFFTTG--DTVCPGNFALWDLTLGLNWIQKHIESFGGDPGNITI 202

  Fly   191 FGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSM------ELNRLPQMEYRLAKHLGYEGDNVDS 249
            ||.|:|:..|.||..||.|..||:|.|:::|.::      ..|...::.|..|:||||:|.|  |
 Worm   203 FGQSAGAACVDLLALSPHSRDLFNRVIVMSGGALCEYAVRTANSQAKVCYEFARHLGYDGTN--S 265

  Fly   250 QVLEFLLKADPALIVSADFFTPLEKRQGHNMP------FKPSIESYSTPNAVLLAEPIDLQRTTW 308
            |.|...:|:.|        ...:||..|..:|      :.|:::....|.:      :|..| ..
 Worm   266 QTLFNWMKSKP--------LEEIEKMNGFQVPASGILAWTPNLDDDFFPKS------LDELR-IG 315

  Fly   309 SNRIPIILGANSGEGMSIFSFVKMNPS--------WLKE---------FQCNPERVLPWTLRNRC 356
            :.:..|::|....||: .|.|:..:|:        ::.|         |:....:::.:..||..
 Worm   316 APKKDIMMGFAEHEGL-FFEFLIKDPTPPLEALKLYVNEYYKKDTGDHFEATRNKIIEFYSRNVE 379

  Fly   357 DPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHG-FVHAMDRLIQSRLTYGQAPTYLYRF 420
            |..: :...:.||....:|               |||.| |.:|     ::.|.:|. ..:||.|
 Worm   380 DTDE-KSTKERLIDFVGDA---------------LFTAGVFDNA-----KNCLKHGN-NVWLYIF 422

  Fly   421 DFDSPDFNFYRIRFMGKEQRGVG------------HVDELGYIFKLPATFKLDKSRPEFTAIRRL 473
            |:.:|.              |.|            |..:|.|:...........:..|...|.::
 Worm   423 DYCNPS--------------GFGNQEEFMTFVAPTHCTDLRYVLGEGLYSDFQPTEEEHKMIEKM 473

  Fly   474 VAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEELKFIPQPEM------PKLKFFD 530
            ..::..||...:||   .....:|:..|....|....||     .|:.:|      .::||.:
 Worm   474 TTIYSNFAKYGNPN---EHGSSEWEKFTLDNPRRHFQIS-----YPRGKMRNDYHPDRMKFLE 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	146/580 (25%)
		Aes	<104..>219	CDD:223730	50/119 (42%)
cest-28	NP_504691.2	COesterase	17..516	CDD:278561	144/569 (25%)
		Aes	<112..>222	CDD:223730	45/114 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28578
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830