Protein Alignment alpha-Est4 and cest-31

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 153/573 - (26%)
• Similarity: 248/573 - (43%)
• Gaps: 143/573 - (24%)

  Fly    11 VVQTTHGKVRGILLKSLY---DEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKC 72
            |:.:|.|.|:|    :||   :|:.:.:.|||||.||:|.||||:|.....|...|||:|...:|
 Worm    16 VLNSTCGPVQG----NLYRHGNEEVHGYLGIPYAQPPIGILRFKKPVSADVWTETRDCTKYGPRC 76

  Fly    73 ---------LQVSTLTKEVEGSEDCLYLNI-----SVKTLNGDPMPVMVYIHGGAFKGGDSSRRA 123
                     ||:.  ..::....:||.||:     .:|  .....|||::||||.|:...|....
 Worm    77 PPSGMLYENLQLP--NTDIPDEANCLSLNVFCPQWEIK--QSAKHPVMIFIHGGGFELSASKDYC 137

  Fly   124 WGPDYFMK-----ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNG 183
               ||.:.     ::|:.:::.:|:|.||||:..|....  ||.||.|:.|||:|:..:.::|.|
 Worm   138 ---DYSLSGTLPLKDVIVVTVNYRVGALGFLTTGDDSCR--GNFGLWDLTLALKWVSTHISSFGG 197

  Fly   184 DPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG-----FSM---ELNRLPQMEYRLAKHL 240
            ||:.:|:||.|:|::...||..||.|..|||:.|:::|     |::   |...|..|||  |:..
 Worm   198 DPKNVTLFGQSAGAVCADLLNLSPYSRDLFHKLIIMSGSAHVPFAIRTEENQALVCMEY--ARSR 260

  Fly   241 GYEGDNVDSQVLEFLLKADPALIVSADFFTPLEK---RQG--H----NMPFKPSIESYSTPNAVL 296
            |:.|.. .:::|||...            .|:||   :.|  |    ::.|.|:::....|
 Worm   261 GFSGSG-SAELLEFFEN------------LPIEKLLEKTGLKHTVSIDLSFAPNLDGDFFP---- 308

  Fly   297 LAEPI-DLQRTTWSNRIPIILGANSGEGMSIFSFV-------------KMNPSWLKEFQCNPERV 347
              :|: :|:|.|  .:.|:|:|....||: |.:|.             ::...:..:...|||.|
 Worm   309 --KPLEELRRET--RKKPVIVGMMEDEGL-ITAFADGDFTTCEENFKRRVESEYRGDVVENPENV 368

  Fly   348 LPWTLR---NRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLT 409
            ....:.   |.||..:.|:                        ||:...|...:|...|....|.
 Worm   369 QKNIMNFYTNYCDESEERK------------------------LVDYIGHSVYNAGVLLSAESLA 409

  Fly   410 YGQAPTYLYRFDFDSPD----------FNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSR 464
            ......|.|.|||.:||          |            :|..|..||.||.......|.|.:.
 Worm   410 RAGNCVYFYVFDFWNPDGFGPVGSIVPF------------KGAAHCSELRYIIGEGVYSKFDANE 462

  Fly   465 PEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISE-ELK 516
            .:...:..:..||..||...:||.|   .:.:|:..|...:...::.:: |:|
 Worm   463 KDLKMMEYMTTMFTNFAKYGNPNIP---GVTNWETYTEGSRHFHIDSTDSEMK 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	153/573 (27%)
		Aes	<104..>219	CDD:223730	46/119 (39%)
cest-31	NP_504692.3	COesterase	16..522	CDD:278561	153/573 (27%)
		Aes	<112..>211	CDD:223730	37/105 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28578
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.830