Protein Alignment alpha-Est4 and cest-30

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 596
• Identity: 148/596 - (24%)
• Similarity: 239/596 - (40%)
• Gaps: 146/596 - (24%)

  Fly     7 EDAPVVQTTHGKVRGILLK-----SLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCS 66
            :::.::....|.:||.:.|     .:.|    .:.|||:|..|:|.|:||:|...:.|...|||.
 Worm    29 KNSQILNAPCGPIRGNIYKHKNGTKIVD----GYLGIPFAKAPVGALKFKKPVAAEKWTEPRDCY 89

  Fly    67 KPLSKCLQV---STLTKEVEGS---EDCLYLNISVK--TLNGDP--MPVMVYIHGGAFKGGDSSR 121
            :....|.|.   :.||.:...:   |:||.||:...  .|...|  :||:|||:||.::.|.:|
 Worm    90 EYGPGCPQTGRFAALTAKSTAAFAEENCLTLNVFAPRWKLAEFPKGLPVLVYIYGGGYEIGFTS- 153

  Fly   122 RAWGPDYFMK-----ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANF 181
              :..||.:.     ::|:.:::.:||||||||::.|....  ||.||.|..|||:|::.|.|:|
 Worm   154 --YMDDYSLTGTLPLKDVIVVTMNYRLGPLGFLTIADGIAN--GNYGLWDQTLALQWVQDNIASF 214

  Fly   182 NGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG--FSMELNRLPQMEYRLAKHL---- 240
            .|:||.:|:.|.|:|:.:...|..||.|..||.|:|.::|  |.....|...:|..:.|..
 Worm   215 GGNPESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTAFCNFAIRPKDVEVGVCKEFAQFQ 279

  Fly   241 GYEGDNVDSQVL-EFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQ 304
            ||.|  .|||.| ::.:..:.:.......|   :......:||.|:.:....|      :|.|:.
 Worm   280 GYTG--TDSQSLFDWYMAQNVSKFKEVAGF---QSTAAGAVPFIPNFDGDFFP------KPFDIL 333

  Fly   305 RTTWSNRIPII-LGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQAL 368
            |.....:..:| :......||.||     ||.:...:             |..:.......|..:
 Worm   334 RREAPKKDALITVVTMESVGMIIF-----NPLFANAY-------------NNFEGFINETYGPDV 380

  Fly   369 IHHFCE------------------AHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPT 415
            ..::.:                  |..:...||:.:..|  |..|.:.|    ::|.:.||. ..
 Worm   381 TDYYADVKKKLTGFYLKDVNASDKATVNRRVVDYVSDSV--FNSGTLDA----VKSYVKYGN-KV 438

  Fly   416 YLYRFDF-------------------DSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLD 461
            ||..|::                   .|.||.:|   |...........||...:..:..|
 Worm   439 YLGSFNYFNDATKDMVELMQPFKEASHSSDFKYY---FGSGVMANFTPTDEEMEVMDMSGT---- 496

  Fly   462 KSRPEFTAIRRLVAMFVQFAATSDPNAPL-TKSLVDWKPVTRFGKRMVLNISEELKFIPQPEMP- 524
                       |:|.||::   .|||... ||   .|||.|.....|...|.     .|..||.
 Worm   497 -----------LMANFVKY---GDPNGKSGTK---PWKPYTILKPNMYYKID-----YPTCEMSD 539

  Fly   525 -----KLKFFD 530
                 :|:.:|
 Worm   540 NFQNGRLRIYD 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	147/593 (25%)
		Aes	<104..>219	CDD:223730	48/119 (40%)
cest-30	NP_504407.1	COesterase	31..539	CDD:278561	146/581 (25%)
		Aes	<122..>230	CDD:223730	41/112 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157275
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.750