Protein Alignment alpha-Est4 and ace-1

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_510660.1
• Gene: ace-1 / 181706
• WormBaseID: WBGene00000035
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 506
• Identity: 136/506 - (26%)
• Similarity: 233/506 - (46%)
• Gaps: 91/506 - (17%)

  Fly    35 FDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQV----------STL-TKEVEGSEDC 88
            |.|||:|.||:|.||||:|...:||....:.:.|.:.|:|.          ||: ....:.||||
 Worm    45 FQGIPFAEPPVGNLRFKKPKPKQPWRIPLNATTPPNSCIQSEDTYFGDFYGSTMWNANTKLSEDC 109

  Fly    89 LYLNISV--KTLNGDPMPVMVYIHGGAFKGGDSSRRAW-GPDYFMKENVVYISIGHRLGPLGFLS 150
            ||||:.|  |......:.|||:::||.|..|.::...: |....::|||:.:::.:|:...|||.
 Worm   110 LYLNVYVPGKVDPNKKLAVMVWVYGGGFWSGTATLDVYDGRILTVEENVILVAMNYRVSIFGFLY 174

  Fly   151 LNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHR 215
            :|.|  |.|||.|:.|.:||::|:..|...|.||..|||:||.|:|:.:|.:.:.||:|...|||
 Worm   175 MNRP--EAPGNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHMLSPKSAPYFHR 237

  Fly   216 AILLAGFSMELNRLPQMEYRLAK-----------HLGYEGDNVDSQVLEFLLKADPALIVSADFF 269
            ||:.:|.:.....:...:..||:           ::.....:.| ::|:...:|| |..:..:.:
 Worm   238 AIIQSGSATSPWAIEPRDVALARAVILYNAMKCGNMSLINPDYD-RILDCFQRAD-ADALRENEW 300

  Fly   270 TPLEKRQGHNMPFKPSIE-SYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGM--------S 325
            .|:  |:..:.|:.|.:: .:...||....:..:.::|      .::.|:|..|.:        .
 Worm   301 APV--REFGDFPWVPVVDGDFLLENAQTSLKQGNFKKT------QLLAGSNRDESIYFLTYQLPD 357

  Fly   326 IF---------SFVKMNPSWLKEFQ-CNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHEL 380
            ||         .|:|....|:|..: ..|.::|      :|      ||..|.:.|  |....:|
 Worm   358 IFPVADFFTKTDFIKDRQLWIKGVKDLLPRQIL------KC------QLTLAAVLH--EYEPQDL 408

  Fly   381 TV---DHTNGLVELF-THGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQRG 441
            .|   |..|.:.::. .:.|..:::.:..:...:| ..||.|.|...:....:       .|..|
 Worm   409 PVTPRDWINAMDKMLGDYHFTCSVNEMALAHTKHG-GDTYYYYFTHRASQQTW-------PEWMG 465

  Fly   442 VGHVDELGYIFKLPATFKLDKSRPEFT-----AIRRLVAMFVQFAATSDPN 487
            |.|..|:.:||..|    |::.|..:|     ...|.:..:..||.|.|||
 Worm   466 VLHGYEINFIFGEP----LNQKRFNYTDEERELSNRFMRYWANFAKTGDPN 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	136/506 (27%)
ace-1	NP_510660.1	Esterase_lipase	20..543	CDD:238191	136/506 (27%)