Protein Alignment alpha-Est4 and cest-13

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_741921.1
• Gene: cest-13 / 181493
• WormBaseID: WBGene00010116
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 605
• Identity: 154/605 - (25%)
• Similarity: 222/605 - (36%)
• Gaps: 170/605 - (28%)

  Fly    12 VQTTHGK--VRGILLKSLYDEQFY--AFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKC 72
            |||.:|.  :|||       :..|  :|.||.||.||:|..||.....|.| .|:.:.....:.|
 Worm    27 VQTPNGSATIRGI-------QHTYGTSFRGIRYAQPPVGLFRFGAARRLDP-VGLVEAQAYGNIC 83

  Fly    73 LQVSTLTKEVEGSEDCLYLNISV--KTLNGDPMPVMVYIHGGAF-KGGDSSRRAWGPDYFMKENV 134
            :|....|..    ||||::|:..  .......:||.||||||.| :||.:......|:...|..:
 Worm    84 VQGDGRTSH----EDCLFINVYTPNNVTQASKLPVYVYIHGGGFVEGGGNMGAGIYPNLVNKGPI 144

  Fly   135 VYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMT 199
            |.:||.:||||.||.|..  .:..|||..:.|.|.||.|::...:.|.|||.|:||.|.|||:..
 Worm   145 VMVSINYRLGPFGFFSTR--QMTAPGNWAISDWIEALNWVQRYISFFGGDPNRVTIGGQSSGAEA 207

  Fly   200 VQLLLASPQSEGLFHRAILLAGFSM--------ELNR--LPQMEYRLAKHLGYEGDNVDS--QVL 252
            |..|..:|.::.||.::|..:|.:.        |..|  ..|:..:|......:.||..|  .:|
 Worm   208 VSTLTLTPLAKNLFKQSIHESGSAFGAAVMSYSEKTRSTSKQLSIKLGCATSDQWDNGQSFGTIL 272

  Fly   253 EFLLKADPALIVSADFFTPLEKRQGHNMPFKPSI---ESYSTPNAVLLAEPIDLQRTTWSNRIPI 314
            ..|.......||:||...|     ||.|  |.||   ..|.|.....||    |||....|   :
 Worm   273 TCLRNVTYDKIVAADNSLP-----GHRM--KWSIVQDNKYLTQRLEYLA----LQRDPKKN---V 323

  Fly   315 ILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAH--G 377
            ::|             .::..|           |.|.:.|             ::|:...:|  .
 Worm   324 LIG-------------DVHDEW-----------LGWEMNN-------------VLHNINSSHNTA 351

  Fly   378 HELTVDHTNGLVELF------------------THGFVHAMDRLIQSR----------------- 407
            |::. |..:|..|:.                  ..|:.....|..::|
 Worm   352 HQMR-DDLSGSYEMTYWDNKQSVLVAADNKYINNQGWTDDNHREWEARRIQLWSEMVFIGPTLRD 415

  Fly   408 ---LTYGQAPTYLYRFDFDSP-------DFNFYRIRFMGKEQRGVGHVDELGYIFK-----LPAT 457
               ..|.:...|||..|:.||       |..|          ||..|..||.|||.     ...|
 Worm   416 AAYFQYMKNNVYLYSLDWLSPPALPLVTDPLF----------RGCEHTWELQYIFSTSCNGFTCT 470

  Fly   458 FKLDKSRPEFTAIRRLVAMFVQFAATSDP---NAPLTKSLVDWKPVTRFGKRMVLNISEELKFIP 519
            .:.:..|..||      ..::.|....:|   .:||....:......||           |.|.|
 Worm   471 AQDEILRNYFT------TTWLNFIIGGNPTPAGSPLPFKWLAMDSTNRF-----------LSFSP 518

  Fly   520 QPEMPKLKFFDRLYEMAGVP 539
            .|:|......|.::.:...|
 Worm   519 NPKMQPHYHPDSMFWVCTAP 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	152/593 (26%)
		Aes	<104..>219	CDD:223730	48/115 (42%)
cest-13	NP_741921.1	Abhydrolase	22..510	CDD:304388	145/564 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000