DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est4 and T09B9.1

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:NP_001024899.1 Gene:T09B9.1 / 181188 WormBaseID:WBGene00011642 Length:431 Species:Caenorhabditis elegans


Alignment Length:440 Identity:91/440 - (20%)
Similarity:147/440 - (33%) Gaps:149/440 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 YNEDAPVVQTTHGKVRGILLKSL---------YDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWH 60
            :::.:.:||.|.|.: .:|.|||         .|.:::.::|.|..|                  
 Worm    67 FSKASSMVQWTRGAL-NLLSKSLGLMVNTHGQIDIKWHVWNGTPVKV------------------ 112

  Fly    61 GIRDCSKPLSKCLQVSTLTKEVEGSEDCLYLNISVKT-LNGDPMPVMVYIHGGAFKGG-----DS 119
                                         |..|:.|| .||    .:::||||.|..|     ||
 Worm   113 -----------------------------YQPINNKTATNG----AVIFIHGGGFALGNVEMYDS 144

  Fly   120 --SRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWI-RANAANF 181
              .|.|:      :...::|||.:||         .|:...||  |:.|...|:..: ...|..|
 Worm   145 LVKRMAF------EMRTLFISIEYRL---------SPETVFPG--GIMDCEAAIEHLFEFGAVQF 192

  Fly   182 NGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG--------------------FSMEL 226
            ..|..:|.|.|.|:|.....::.....:...|.:   |||                    |...|
 Worm   193 GIDTSKIVIMGDSAGGNMATVIAQRRAARNAFPK---LAGQVLIYPLLQMADLQTVSYRYFHSRL 254

  Fly   227 N--RLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESY 289
            |  .|...|..:..::.|.|.|:|.:.  :|:   |::|.:......|:......|.::..||| 
 Worm   255 NGYALVDPESVVYYYMFYAGINMDEKA--YLV---PSVISNGHVSDSLKSEVDKMMEYEHIIES- 313

  Fly   290 STPNAVLLAEPIDLQRTTWSNRIPIILGAN-SGEGMSIFSFVKMNPSW---LKEFQCNPERVLPW 350
                          .||..::.||...... |.|...:......||.:   :|:...|    ||.
 Worm   314 --------------TRTYKNHSIPCRWPVRPSFEAQQLMEPFLNNPDFSPLMKKDVSN----LPP 360

  Fly   351 TLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAM 400
            |:...|:....|..|....|....:.....|:::.||.         |||
 Worm   361 TMVVTCEFDILRDEGLIYAHRLESSGVPTTTINYKNGF---------HAM 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 91/437 (21%)
T09B9.1NP_001024899.1 Abhydrolase_3 126..405 CDD:400284 73/329 (22%)

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