Protein Alignment alpha-Est4 and cest-1.1

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 140/585 - (23%)
• Similarity: 229/585 - (39%)
• Gaps: 144/585 - (24%)

  Fly    14 TTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQVSTL 78
            |..||:..|....|.::....|.|||:..||:|.||:::|...|.|.|:...::..|.|:..:|.
 Worm    25 TIEGKILNISYSPLGNQSATVFLGIPFVEPPIGDLRYRKPRPPKSWEGVLVTNEYKSACMSNATK 89

  Fly    79 T-KEVEG---SEDCLYLNISVK--TLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMK------ 131
            | |...|   ||||||||:...  .|......||:.:|||.:.  ..|...:.|:..:.
 Worm    90 TYKNKFGGPISEDCLYLNVLTNEYCLENKNCSVMMIVHGGGYL--TESASTFNPEILINNFVGQG 152

  Fly   132 ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSG 196
            .|:|.::..:|||...|...|..  ....|.||.|:|.::.|:|....||.|:..|||:.|||:|
 Worm   153 RNIVVVTFNYRLGLFSFGQFNGD--RGDKNFGLYDMIESVNWVRREIENFGGNKNRITLAGHSAG 215

  Fly   197 SMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPA 261
            :..:....:||.::||.|:.|:::.        |..  .::|...::|..|.:|::..|
 Worm   216 ASMIVAFTSSPLTKGLVHQQIIMSA--------PMT--NMSKKSNFKGMTVMAQMVGCL------ 264

  Fly   262 LIVSADF-FTPLEKRQGHNMPFKPSIESYS-----TPNAVLLAEPIDLQRTTWSNRIPIILGA-- 318
               |.:. |..|.:.|..|        :||     :...:|.|:...||.:|:      .|||
 Worm   265 ---SEEIGFNKLSEEQVEN--------TYSCLRKKSAQQILDAQLWLLQNSTY------FLGAPP 312

  Fly   319 -----------NSGEGMSIF----------------SFVKMNPSWL-KEFQCNPERVLPWTLRNR 355
                       |.....||:                |:: ::|::. |:.:         .|.|.
 Worm   313 IDEHFLTDYPENLYASKSIYPINTLIGTTTLEVEESSYI-IDPAFADKKVE---------LLENL 367

  Fly   356 CDPGQRRQLGQALIHHFCEAHGHELTVDHTNG--------LVELFTHGFVHAMDRLIQSRLTYGQ 412
            ||     .:|..| :...|....:....:.||        .:|.:|.....|...      |.|.
 Worm   368 CD-----HIGYVL-YEEPETFSKKCQKQYMNGNSSMNLSNEMEFYTPAIDFADSH------TSGN 420

  Fly   413 APTYLYRFDF--DSPDFNFYRIRFMGKEQRGVGHVDELGYIFK------LPATFKLDKSRPEFTA 469
            ...:||.:|:  ..|.::.|      .|.|...|.::|.|:|.      .|..:.::|      .
 Worm   421 TKVFLYSYDYRGAGPAYDRY------LEVRSPHHSEDLIYVFGTHRGIFAPKDYIIEK------I 473

  Fly   470 IRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEELKFIPQPEMPKLKFFDRLYE 534
            ...:.|.||.|      ..||......|...|:..:...| |:.:..|| .|.| :..::...||
 Worm   474 YSGMFADFVNF------ENPLPSGDQKWNQYTKENREHFL-INFDKNFI-TPGM-RDNYYTEAYE 529

  Fly   535  534
             Worm   530  529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	138/578 (24%)
		Aes	<104..>219	CDD:223730	37/120 (31%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:278561	140/585 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740