Protein Alignment alpha-Est4 and cest-17

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_505114.1
• Gene: cest-17 / 179198
• WormBaseID: WBGene00019477
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 153/565 - (27%)
• Similarity: 242/565 - (42%)
• Gaps: 143/565 - (25%)

  Fly    10 PVVQTTHGKVRGILLKS-LYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPW-HGIRDCSKPLSKC 72
            |.|.|.:|.:.|...|| :...:::.|.||.|..||....||::|..::.| |...|.:...:.|
 Worm    22 PKVTTPYGPIVGFEHKSTVTGSKYHVFLGIRYGNPPDHIYRFQKPEPVEKWPHINHDATHFRASC 86

  Fly    73 LQV--STLTKEVEGSEDCLYLNI-SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAW--GPDYFMKE 132
            :..  |.|.::|..|||||:||| :........:||:|:||||.|:.||:|...:  ..|.|:.:
 Worm    87 IPSLRSELEEQVNYSEDCLFLNIVTPPDAKEKKLPVLVFIHGGGFQFGDTSMIGYQKAADNFVSK 151

  Fly   133 NVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGS 197
            :::::||.:|||||||.:..|.  |:|||.||.|..|||:::.....:|.|||:|||:.|||:|:
 Worm   152 DIIFVSIQYRLGPLGFFTTGDS--EIPGNMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHSAGA 214

  Fly   198 MTVQLLLASPQSEGLFHRAILLAG--FS-MELNR-LPQMEYRLAKHLGYE-------GDNVDSQV 251
            .:|..||.||.|:.||.:||.|:|  || ..|:| :.....:|||..|..       .|.::.:.
 Worm   215 ASVSALLYSPHSDHLFSQAIQLSGSIFSESNLDRNVVDDSRKLAKAAGCPQEDSKELRDCIEIRT 279

  Fly   252 LEFLLKADPAL--------------IVSADFFTPLEKRQGHNMPFK------PSIES-YSTPNAV 295
            ::.||.|..::              ....|||....::.....|.|      .|:|| .|....|
 Worm   280 VDELLDAMESIGELLPGPRTKKFHPYFDKDFFPYDIEKMSRKAPKKRTMQGLVSLESGLSVLYPV 344

  Fly   296 LLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQ 360
            .||:.:.:.:.:||          :....::..|::...:..:||.....|.
 Worm   345 KLAKLLGVPKESWS----------TYSKDNLVDFIRSQVAVEQEFGTASARF------------- 386

  Fly   361 RRQLGQALIHHFCEAHGHELTVDHTNGLVE-------------LFTHGFVHAMDRL--------- 403
                                     :||||             .:.:.|.:.:..|
 Worm   387 -------------------------SGLVEEFYLSGPMTGNSSFYLNAFANLLSDLQYNIPTLHE 426

  Fly   404 IQSRLTYGQAPTYLYRFDFDS-----PDFNFYRIRFMGKEQRGVGHVDELGYIFK------LPAT 457
            ::.:|.:|. .||||..|:||     |....          :|..|..||.|:|.      :|..
 Worm   427 VELKLQHGW-DTYLYIIDYDSETTKDPTHPI----------KGPFHASELRYLFNFNGMDTIPFN 480

  Fly   458 FKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTR 502
            .| ||....:     .|...|.|..|..|:   ||:|: |..|::
 Worm   481 DK-DKKFENY-----FVNAIVNFINTGTPS---TKALL-WPAVSK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	153/565 (27%)
cest-17	NP_505114.1	COesterase	22..542	CDD:395084	153/565 (27%)