Protein Alignment alpha-Est4 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 142/533 - (26%)
• Similarity: 227/533 - (42%)
• Gaps: 112/533 - (21%)

  Fly     7 EDAPVVQTTHGKVRGILLKSLY---DEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKP 68
            ::..|...:.|.:||    ::|   |:....:.|||:|..|:|.||||:..:.:.|....||.|.
 Worm    12 KNTEVFNASCGPIRG----NVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKY 72

  Fly    69 LSKC--------LQVSTLTKEVEGSEDCLYLNI------SVKTLNGDPMPVMVYIHGGAFKGGDS 119
            ...|        |.||..|......::||.||:      |.:..||  .|||||.:||.|:.|.|
 Worm    73 GPGCPQSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNG--FPVMVYFYGGGFEVGFS 135

  Fly   120 SRRAWGPDYFMK-----ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAA 179
            |   ...||.:.     ::|:.::..:|:|||||.:..| |: ..||.||.|..|||:|::.:..
 Worm   136 S---MFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGD-DV-ARGNWGLWDQALALQWVQKHIK 195

  Fly   180 NFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG-----FSMELNRLPQMEYR-LAK 238
            :|.|||..:||.|.|:|..:|..|..||.:...|.:.|.::|     |.:....:..:.:| .|.
 Worm   196 SFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFAN 260

  Fly   239 HLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMP------FKPSIESYSTPNAVLL 297
            |.||.| |....:|::....|..:.:         |.:|:..|      |.|:.:....|
 Worm   261 HHGYTG-NDSKSLLQWYQSQDSEIFL---------KAEGYKCPASGMFSFVPNFDGDFFP----- 310

  Fly   298 AEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVL-----PWTLRNRCD 357
             :|.|..|.. :.::..|:.....||:....|.        ..|..|:::|     |..:|||
 Worm   311 -KPFDELRKE-APKLGAIVSIGEYEGLGFEDFY--------AGQKTPQQMLSAALGPEVVRNR-- 363

  Fly   358 PGQRRQLGQALIHHFCEAH----GHELTVDHTNGLVELFTHGF--VHAMDRLIQSRLTYGQAPTY 416
                    :.::....|::    |:|...:....|||:|...:  |.|.| .::|.:.||.. .|
 Worm   364 --------EEVVKRAAESYLKNGGNENEENIAKTLVEIFGDYYFSVGAFD-TVRSLVKYGNT-VY 418

  Fly   417 LYRFDFDSPDFNFYRIRFMGKEQ--RGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLV----- 474
            ||.|::.:|:...    ..||.:  ....|..:|.|||        .:...||:...|.|
 Worm   419 LYSFNYFNPNTPI----VFGKNRPFNAANHGSDLRYIF--------GEGTGEFSKEDRQVMDMMG 471

  Fly   475 AMFVQFAATSDPN 487
            .....||...:||
 Worm   472 TYHTNFAKYGNPN 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	142/533 (27%)
		Aes	<104..>219	CDD:223730	46/119 (39%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	142/531 (27%)
		Aes	<105..>239	CDD:223730	50/140 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157292
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750