Protein Alignment alpha-Est4 and cest-32

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 588
• Identity: 156/588 - (26%)
• Similarity: 247/588 - (42%)
• Gaps: 144/588 - (24%)

  Fly    11 VVQTTHGKVRGILLKSLYDEQFY-AFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQ 74
            |:..:.|.|.|.:.:  :|::.. .:.|||:|..|:..||||:|.:.:.|....:|.|....|.|
 Worm    16 VLNASCGPVIGNIYR--HDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLNCHKYGPGCPQ 78

  Fly    75 VSTLTKEV------EGSED-CLYLNI------SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGP 126
            ...:...:      |.:|| ||.|||      |.:..||  :|:|||.|||.|:.|.||   ...
 Worm    79 SGHMISNLLPPGYREFAEDNCLNLNIFAPSWKSEEFPNG--LPIMVYFHGGGFEIGFSS---MFD 138

  Fly   127 DYFMK-----ENVVYISIGHRLGPLGFLSLNDPDLEVP-GNAGLKDVILALRWIRANAANFNGDP 185
            ||.:.     ::|:.::..:|:|||||::..|   ||. ||.||.|..|||:|::.:..:|.|:|
 Worm   139 DYSLSGTLPLKDVIVVTANYRVGPLGFMTTGD---EVSRGNYGLWDQTLALKWVQEHIKSFGGNP 200

  Fly   186 ERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAG-----FSMELNRLPQMEYR-LAKHLGYEG 244
            ..:|:.|.|:|.::..||..||.|..||||.:.::|     ||:.........:| .|||.||||
 Worm   201 NIVTVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHHGYEG 265

  Fly   245 DNVDSQVLEFLLKADP--ALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPID-LQRT 306
            ::.:| :||: .|:.|  ....:|.|    ||:....:.|.|:.:....|      :|.| |.|.
 Worm   266 EDSES-LLEW-YKSQPLSKFQETATF----EKKASGFLTFIPNFDGDFFP------KPFDELSRE 318

  Fly   307 TWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHH 371
              :.::..:...:..||:          .:|..||         :.||..|. .:...|..::
 Worm   319 --APKLDAMATVDEYEGL----------GFLTMFQ---------SRRNDMDI-IKSSFGSDVV-- 359

  Fly   372 FCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRL---------------------TYGQAPT 415
                   |..||....::|.:........|:.::.||                     .|| :..
 Worm   360 -------ENAVDVQKRIMEFYMKNIDKNDDKAVEKRLIQLISDSWFNIGALETVKTSTKYG-SNA 416

  Fly   416 YLYRFDFDSPDFNFYRIRFMGKEQ--------RGVGHVDELGYIFKLPATFKLDKSRPEFTAI-- 470
            ||..||:    :|      ||...        :...|..||.|:.. ....|......||..|
 Worm   417 YLGSFDY----YN------MGSNDPYATWFPFKAANHGSELKYMLG-EGMGKFSPIEEEFKVIDM 470

  Fly   471 -RRLVAMFVQFAATSDPNAP-LTKSLVDWKPVTRFGKRMVLNISEELKFIPQPEM------PKLK 527
             ..|.|.||::...:..|.| |.|.....||.:.|          ::.: |:.||      .:||
 Worm   471 MGTLTANFVKYGNPNGINGPELWKKYTPEKPYSYF----------KIDY-PKSEMRDNFQDGRLK 524

  Fly   528 FFD 530
            .|:
 Worm   525 LFE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	155/585 (26%)
cest-32	NP_504397.1	COesterase	16..519	CDD:395084	153/578 (26%)