Protein Alignment alpha-Est4 and ges-1

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 158/602 - (26%)
• Similarity: 259/602 - (43%)
• Gaps: 144/602 - (23%)

  Fly    10 PVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGI-------RDCSK 67
            |:|:|.:|||.||..:..  |.|.|   ||:|.||:..|||::|....||..:       .||:.
 Worm    18 PIVETNYGKVEGIEYEGA--EVFLA---IPFAKPPVDDLRFEKPVAPDPWEDVYPATQYRNDCTP 77

  Fly    68 PLSKCLQVSTLTKEVEGSEDCLYLNISVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMK- 131
            ......|.|:.:     .||||.||| :|....:.:||:.:||||.::.|.:|:.  |.::|.|
 Worm    78 HYRLVAQFSSYS-----GEDCLTLNI-IKPKKAEKLPVLFWIHGGGYEIGSASQH--GYEFFAKR 134

  Fly   132 ---ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGH 193
               :.|:..::.:|||.:||.|....|  |.||.||.|...||.::::|..||.|||.:|||:|:
 Worm   135 YASQGVIVATVQYRLGFMGFFSEGTSD--VQGNWGLFDQAAALEFVKSNIENFGGDPNQITIWGY 197

  Fly   194 SSGSMTVQLLLASPQSEGLFHRAILLA-----GFSMELNRLPQMEYRLAKHLG--YEG------- 244
            |:|:.:|..|..||.:...:.:||:::     |::...| :.:...:||:.||  :.|
 Worm   198 SAGAASVSQLTMSPYTRDSYSKAIIMSASSFVGWATGPN-VVETSKQLAEILGCPWPGAKECMKK 261

  Fly   245 -------DNVDSQ-----VLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLL 297
                   |.::.|     .:: :|:..|  ::..||.|                   ..|..::.
 Worm   262 KSLHEIFDAIEVQGWTTGTID-ILRWSP--VIDGDFMT-------------------KNPEELIK 304

  Fly   298 AEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPE---------------RV 347
            ..|:.          |.::|.::.|| |.|:.:.|. ..:.:|..:||               |.
 Worm   305 ESPVK----------PTLIGMSNKEG-SYFAALNMG-RVIADFGLSPEDMPKVDEEFISEIIGRK 357

  Fly   348 LPWTLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYG- 411
            |.:..|.    |:.|:.....|..|....|....|...||.       :|.....|: |.:|:.
 Worm   358 LLYNNRY----GENREKVWNDILDFYVKQGKPAEVKDLNGF-------YVDRYSELL-SDITFNV 410

  Fly   412 ------------QAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLD-KS 463
                        :.|.:.||  .|..|.|.:: :.:.::.||..|.:|..|:|.:|...|:| |.
 Worm   411 PILREITSRVERKTPVWTYR--MDHYDKNIWK-KHIPEQARGSPHANEYHYLFDMPVMAKIDMKK 472

  Fly   464 RPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNI-----SEELKFIPQPEM 523
            .|:......|:.|.:.||.|..|..    ..|:|:||:.......|||     |.|.....:|
 Worm   473 EPDSWIQNDLIDMVISFAKTGVPQI----EDVEWRPVSDPDDVNFLNIRSDGVSIEHGLFQEP-- 531

  Fly   524 PKLKFFDRLYEMAGVPL 540
              |.|::.|.:..|..|
 Worm   532 --LAFWNELRQREGFDL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	154/589 (26%)
		Aes	<104..>219	CDD:223730	45/118 (38%)
ges-1	NP_503411.1	COesterase	18..535	CDD:278561	154/589 (26%)
		Aes	<100..>211	CDD:223730	42/114 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810