Protein Alignment alpha-Est4 and cest-10

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 592
• Identity: 137/592 - (23%)
• Similarity: 229/592 - (38%)
• Gaps: 137/592 - (23%)

  Fly     8 DAPVVQTTHGKVRGILLKSLYDE--QFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLS 70
            |:.:|:|:.||:.|       |:  .|:.|..||:|.||||.|||::|...:.|:|:|:......
 Worm    20 DSVIVETSLGKLNG-------DQIGNFHLFKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKDYGP 77

  Fly    71 KCLQVSTLTKEVEG--SEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFM- 130
            .|:..|:.||.|:.  .||||:|||  |...|......|::|:|||... .||:  ....|.|:
 Worm    78 ACMSNSSTTKTVQKWVDEDCLHLNIFTSETCLKSKNCAVVIYLHGGNLH-YDSA--VMFNDTFLL 139

  Fly   131 ----KENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIF 191
                .:.:|::....|||......:.|..: .|.|..|.|::.|:.:.:::..||.|:.:|.|:.
 Worm   140 HTYASQEIVFVIPAVRLGIFSHFVVEDQSI-APNNLALFDMLQAMEFAKSDIHNFGGNNKRTTLL 203

  Fly   192 GHSSGSMTVQLLLASPQSE---GLFHRAILLAG----FSMELNRLPQME--YRLAKHLGYEGDNV 247
            |||.|.....:|..|.:..   .||.:.|.::.    .::||    |:|  ||.|:|.     |.
 Worm   204 GHSYGGTVASMLSFSTKVNTDLSLFQQYISMSSPTNFDTLEL----QVERTYRFAEHA-----NC 259

  Fly   248 DSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRI 312
            ..:..:|:.|....:.:.    ..|:|:..                    :|.:.:||:......
 Worm   260 LPKNSKFMRKNQKEVYMR----DCLKKKSA--------------------SELLRIQRSLEEAGY 300

  Fly   313 PIILGANSGEGMSIFSFVKMNPSWL----KEFQCNPERVLPWTLRNRCDP---GQRRQLGQALIH 370
            |:..|:           |...|.:.    ::|..:|..:...|...:.:.   ...|.:|:||..
 Worm   301 PVYGGS-----------VMRGPIFQEVLERDFMDSPNNITSLTGCTKYESLVYDHYRNMGKALGF 354

  Fly   371 HFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQ-----APTYLYRFDFDSPDFNFY 430
            ...|....:...|...|.:| |.:........|||.|....:     .|.|.|.:.:
 Worm   355 ENYEEVNEKYRSDSKEGKIE-FDNVKNATQIMLIQIRTRVNKILKKNIPAYHYEYAY-------- 410

  Fly   431 RIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDP-----NAPL 490
                    .:...|.|:|.:|..: ..|..|::..:.....|  :||:.|..|.:|     .|.|
 Worm   411 --------PKHANHTDDLFFIMGV-HPFIQDENEIKLGNFYR--SMFLNFIKTGNPGNGCDGANL 464

  Fly   491 TKSL---VDWKPVTRFGKRMVLNISEE--------------------LKFIPQPEMPKLKFFDRL 532
            ..|.   |:|...|  |:|.|:..:.|                    |:.|.....|..:.|...
 Worm   465 NGSTYFEVNWNETT--GERPVMKNNFEQKILDYWTKNMIEFDREVSLLRNIKSRRQPASRVFSAY 527

  Fly   533 YEMAGVP 539
            |.....|
 Worm   528 YSFMSFP 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	134/580 (23%)
		Aes	<104..>219	CDD:223730	33/122 (27%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	130/556 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156931
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740