Protein Alignment alpha-Est4 and cest-5.2

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 131/553 - (23%)
• Similarity: 222/553 - (40%)
• Gaps: 131/553 - (23%)

  Fly    11 VVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQV 75
            :::|:.|::.|     ....::..|..||:|.||:|||||::|...:.|:|:.:.::....|:..
 Worm    23 IIKTSLGRLEG-----KQSGKYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMSN 82

  Fly    76 STLTKEVEG--SEDCLYLNI--SVKTLNGDPMPVMVYIHGG--AFKGGDSSRRAWGPDYFMKENV 134
            ||.|:..:.  .||||::||  |.|.|......|:||||||  .|.........:..:.|:|::|
 Worm    83 STWTQSPQKWVDEDCLHVNIFTSDKCLKSKDCAVVVYIHGGEIVFDSAVMFNDTFLLESFVKQDV 147

  Fly   135 VYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMT 199
            :.:....|||.....:::|.:: .|.|..|.|:|||..::::...||.||.::||:||||.|...
 Worm   148 ILVIPAFRLGIFSHFTVHDQNI-APNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYGGTI 211

  Fly   200 VQLLLASP---QSEGLFHRAILLAG--FSMELNRLPQMEYRLAKHLGYE-GDNV-----DSQVLE 253
            ..::..|.   |...||.|.|:::.  :...|....:...|:.||.|.. ..|:     .||..:
 Worm   212 ASMMAFSSEINQDLSLFQRIIVMSANQYFDTLEEQIERSDRVVKHAGCSVPTNLARKMNRSQKEK 276

  Fly   254 FLLKADPALIVSADFFTPLEKRQGHN-MPFKPSIESYSTPNA--VLLAEPI-----DLQRTTWSN 310
            :::|.             |:|..|.. :..:.|:|....|:.  ::|..|:     .|:......
 Worm   277 YMMKC-------------LQKLSGMELLSVQRSLEEAGYPDIGNLVLRGPLFPDVTSLEMLESPK 328

  Fly   311 RIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWT-----LRN--RCDPGQRRQLGQAL 368
            .||::.|..                   :|:.:.|....:.     |.|  .||...|:.|...:
 Worm   329 MIPMLAGCT-------------------KFESDDEDETHFIGKHFGLENPIECDEKYRKDLENGI 374

  Fly   369 IHHFCEAHGHELTVDHTNGLV--------ELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSP 425
            .    :...|.   |.|..::        :|..||                 .|.|||.|.:...
 Worm   375 F----DRQNHS---DKTQAIMVPTKLRVDQLRKHG-----------------VPAYLYEFTYPKH 415

  Fly   426 DFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAI-RRLVAMFVQFA------AT 483
            .|                |.|:|.||..: ..|:.|::......: |.::..|::|.      ..
 Worm   416 AF----------------HTDDLYYIMGI-HPFEKDENEEHLEKVYRNMLINFIKFGEPGMGFEM 463

  Fly   484 SDPNAPLTKSLVDWKPVT----RFGKRMVLNIS 512
            ||.|.. |...:.|...|    |..||...||:
 Worm   464 SDLNES-TYFEIYWNETTGQKPRMRKRFEENIT 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	131/553 (24%)
		Aes	<104..>219	CDD:223730	39/119 (33%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	131/553 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156897
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740