Protein Alignment alpha-Est4 and cest-12

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_499576.4
• Gene: cest-12 / 176642
• WormBaseID: WBGene00013540
• Length: 850
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 107/417 - (25%)
• Similarity: 169/417 - (40%)
• Gaps: 99/417 - (23%)

  Fly    12 VQTTHGKVRGILL------KSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWH-GIRDCSKPL 69
            |..:.|.|:|..:      ..||..|..||.||||...|:|.||.:.|..|..:: .:.|.:...
 Worm    37 VSCSQGSVQGRQVNLGNDQSQLYSGQANAFTGIPYCQAPVGNLRLQPPQPLNQFNTTLHDATYFR 101

  Fly    70 SKCLQVSTLTKEVEG---SEDCLYLNI---SVKTLNGDPMPVMVYIHG--GAFKGG-DSSRRAWG 125
            .||.|::.      |   :|||||||:   .....|.: :.|:|.|.|  |...|| |.::....
 Worm   102 PKCPQLNA------GGPTNEDCLYLNVYTPQAGNTNAN-LSVLVLIDGSNGFSNGGCDQNQEKGI 159

  Fly   126 PDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITI 190
            ....::..:|.:::.:|:|.|||.:....  .|..|.|:.|.:.|:|||:....||.|:|.:||:
 Worm   160 ISNLVQRQIVVVTMQYRIGALGFFTTYTN--SVQSNLGMLDQVQAMRWIKTEIVNFGGNPNQITV 222

  Fly   191 FGHSSGSMTVQLLLASPQSEGLFHRAILLAGF---------SMELNRLPQMEYRLAK-------- 238
            .|...|:..|.....||.|:.||::||:.:|.         ::..|  ||::....:
 Worm   223 AGQDDGACAVSAHCLSPMSQNLFNQAIVQSGSVYSCYNPTPAVPTN--PQVQVTTPRPMYDQSNT 285

  Fly   239 ---------HLGYEGDNVDSQVLEFLLKA---DPA--LIVSADFFTPLEKRQGHNMPFKPSIESY 289
                     :.||:...:.|........|   ||:  |..:....:|.:...|.....:..:::|
 Worm   286 GYGNAGYQNNYGYQPQPITSTSSYNSANAQYDDPSQQLAQTLCNISPDQWNNGQTQNIQNCMKNY 350

  Fly   290 ST----------PNAV--------LLAEPIDLQRTTWSNRIPIILGA-------------NSGEG 323
            :.          |||.        .|...|| ..||....||||:|.             |:|:|
 Worm   351 TVDFFVNQQPGGPNATWMIVRDTSFLPGSID-SLTTRRPNIPIIIGTVQDEDADYAFKLINTGKG 414

  Fly   324 MS-------IFSFVKMNPSWLKEFQCN 343
            ..       ||.|.:.|.  |.:.|.|
 Worm   415 SDPNNLDDWIFDFARKNK--LNQTQAN 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	107/417 (26%)
		Aes	<104..>219	CDD:223730	38/117 (32%)
cest-12	NP_499576.4	Abhydrolase	37..>400	CDD:389770	97/374 (26%)
		Abhydrolase	<678..774	CDD:389770

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900